2938169-99-2

PROTAC K-Ras Degrader-4 Chemical Structure
2938169-99-2

Chemical Structure

PROTAC K-Ras Degrader-4

  • CAS No.: 2938169-99-2
  • Formula:C50H60N12O6S2
  • Molecular Weight:989.22

InChIKey: YIBGZBSCYLTBRE-GMDSDUMKSA-N

SMILES: C[C@@]1(C2=NC(C3=NC(N4[C@H](CN(CCC4)CCCCOC5=NOC([C@@H](C(C)C)C(N6[C@@H](C[C@H](C6)O)C(NCC7=CC=C(C8=C(N=CS8)C)C=C7)=O)=O)=C5)C)=NC=C3)=NO2)C9=C(CCC1)SC(N)=C9C#N

Biological Activity: PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway[1].

Cat. No. Product Name Purity Description Pricing
HY-159788 		PROTAC K-Ras Degrader-4 99.01% PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRASG12D in GP5d and degrades KRASG12V in cell SW620 with DC50s of 1 nM and 13 nM. PROTAC K-Ras Degrader-4 inhibits MAPK signaling pathway.
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