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(R)-ACBI-4

(R)-ACBI-4 is an isomer of ACBI-4 (HY-176792). ACBI-4 is a selective GTP-loaded active state of KRAS (KRAS(on)) PROTAC degrader. ACBI-4 has significant anti-proliferative effect and potently degrades multiple KRAS mutants in cancer cells, such as KRASG12R.
(Pink: Ras ligand (HY-162960); Blue: VHL ligand (HY-176917); Black: linker).

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  • CAS 番号: 3097973-97-9
  • 分子式: C50H63N15O4S
  • 分子量:970.20
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • (R)-ACBI-4 Chemical Structure
    (R)-ACBI-4 構造式
CAS 番号: 3097973-97-9
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  • (R)-ACBI-4 Chemical Structure
    (R)-ACBI-4 Chemical Structure
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  • (R)-ACBI-4