1. JAK/STAT Signaling MAPK/ERK Pathway Protein Tyrosine Kinase/RTK
  2. EGFR Raf
  3. Lifirafenib maleate

Lifirafenib maleate  (Synonyms: BGB-283 maleate)

Cat. No.: HY-18957B
Handling Instructions

Lifirafenib (BGB-283) maleate is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively.

For research use only. We do not sell to patients.

Lifirafenib maleate Chemical Structure

Lifirafenib maleate Chemical Structure

CAS No. : 1854985-74-2

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Lifirafenib (BGB-283) maleate is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively[1].

IC50 & Target

IC50: 23 nM (recombinant BRafV600E ), 29 nM (EGFR)[1]

Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Lifirafenib maleate Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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