1854985-74-2
1854985-74-2
Chemical Structure
Lifirafenib maleate
Synonym(s): BGB-283 maleate
- CAS No.: 1854985-74-2
- Formula:C25H17F3N4O3.3/2C4H4O4
- Molecular Weight:652.53
SMILES: O=C1NC2=NC=CC(OC3=CC=C(O[C@@]4([H])[C@]5([H])[C@@H]4C6=NC7=CC=C(C(F)(F)F)C=C7N6)C5=C3)=C2CC1.O=C(/C=C/C(O)=O)O.[1.5]
Biological Activity: Lifirafenib (BGB-283) maleate is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively[1].
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Lifirafenib maleate | Lifirafenib (BGB-283) maleate is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. | |||||||||||||||||||||
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References
Keywords
