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Cat. No.: HY-18957A

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rel-Lifirafenib

Name: rel-Lifirafenib
Brand: MedChemExpress
SKU: HY-18957A
Availability: PreOrder

(Synonyms: rel-BGB-283)

rel-Lifirafenib (rel-BGB-283) is the relative configuration of Lifirafenib (HY-18957). Lifirafenib is a potent Raf Kinase and EGFR inhibitor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1446090-77-2
화학식: C₂₅H₁₇F₃N₄O₃
분자량:478.42

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

rel-Lifirafenib Chemical Structure

CAS No.: 1446090-77-2

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Biological Activity

제품 설명

rel-Lifirafenib (rel-BGB-283) is the relative configuration of Lifirafenib (HY-18957). Lifirafenib is a potent Raf Kinase and EGFR inhibitor^[1].

All Raf Isoforms :

All EGFR Isoforms :

Chemical Information

CAS No. 1446090-77-2
분자량 478.42
화학식 C₂₅H₁₇F₃N₄O₃
SMILES

O=C1NC2=NC=CC(OC3=CC=C(O[C@]4([H])[C@@]5([H])[C@H]4C6=NC7=CC=C(C(F)(F)F)C=C7N6)C5=C3)=C2CC1.[Relative stereochemistry]
Synonyms

rel-BGB-283
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tang Z, et al. BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers. Mol Cancer Ther. 2015 Oct;14(10):2187-97. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

rel-Lifirafenib

All Raf Isoforms

All EGFR Isoforms

Biological Activity

제품 설명

Chemical Information

순도&문서

References

Calculators

Help & FAQs

rel-Lifirafenib Related Classifications

HY-18957A Related Classifications

Bioz

Keywords

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