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  2. CD Antigens
  3. Stem Cell CD Proteins Endothelial cell CD Proteins
  4. VCAM-1/CD106
  5. VCAM-1/CD106 Protein, Human (HEK293, His)

VCAM-1/CD106 Protein, Human (HEK293, His)

Cat. No.: HY-P7777
COA Handling Instructions

CD106 Protein, Human (HEK293, His) is a cytokine-inducible cell surface protein capable of mediating adhesion.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
10 μg $65 In-stock
50 μg $195 In-stock
100 μg   Get quote  
250 μg   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

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CD106 Protein, Human (HEK293, His) is a cytokine-inducible cell surface protein capable of mediating adhesion.


CD106 (VCAM1) serves as a ligand for very late antigen-4 (VLA-4), which is present on leukocytes. CD106 (VCAM1) is a component of the neural stem cell niche that is critical for MSC-mediated immunosuppression and hematopoietic progenitor cell binding. CD106 promotes strong adhesion of leukocytes to the endothelium. Cell-to-cell adhesion mediated by CD106 is known to be critical for T-cell activation and leukocyte recruitment to inflammatory sites, and therefore it plays an important role in evoking effective immune responses. CD106 is highly expressed on chorionic villi (CV)-MSCs, moderately expressed on BM-MSCs, poorly expressed on umbilical cord MSCs, and not expressed on adipose MSCs[1].








P19320 (F25-E698)

Gene ID
rHuCD106, His; Vascular Cell Adhesion Protein 1; V-CAM 1; VCAM-1; INCAM-100; CD106; VCAM1; L1CAM
AA Sequence


Molecular Weight

85-120 kDa


Greater than 95% as determined by reducing SDS-PAGE.


Lyophilized powder.


Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, 2 mM CaCl2, 2 mM MgCl2, 5% Threhalose, pH 7.2.

Endotoxin Level

<1 EU/μg, determined by LAL method.


It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US; may vary elsewhere.


VCAM-1/CD106 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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VCAM-1/CD106 Protein, Human (HEK293, His)
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