1. GPCR/G Protein
  2. Vasopressin Receptor
  3. c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm

c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm is a is a potent, selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.25 and 0.05 nM for hV2R and rV2R, respectively.

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c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm

c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm 화학구조

CAS No. : 1647119-71-8

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제품 설명

c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm is a is a potent, selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.25 and 0.05 nM for hV2R and rV2R, respectively[1].

IC50 & Target

EC50: 0.25 nM (hV2R), 0.05 nM (rV2R)[1]

Cellular Effect
Cell Line Type Value Description References
HEK293 EC50
0.05 nM
Compound: 19
Agonist activity at recombinant rat V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
Agonist activity at recombinant rat V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
[PMID: 31022340]
HEK293 EC50
0.25 nM
Compound: 19
Agonist activity at recombinant human V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
Agonist activity at recombinant human V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
[PMID: 31022340]
HEK293 EC50
530 nM
Compound: 19
Agonist activity at recombinant human V1B receptor expressed in HEK293 cells measured after 5 hrs by luciferase reporter gene assay
Agonist activity at recombinant human V1B receptor expressed in HEK293 cells measured after 5 hrs by luciferase reporter gene assay
[PMID: 31022340]
분자량

1045.71

화학식

C47H69ClN12O9S2

CAS No.
선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

상품명:
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm
Cat. No.:
HY-P1810
수량:
MCE Japan Authorized Agent: