MS1 peptide
MS-1 peptide is a peptide for BH3 profiling. MS-1 peptide triggers higher depolarization of mitochondrial membrane in melanoma cells pre-treated with Encorafenib (HY-15605). MS1 peptide can be used for the research of BRAFV600E melanoma.
For research use only. We do not sell to patients.
- CAS No.: 1875102-20-7
- Formula: C126H197N39O35S
- Molecular Weight:2850.22
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Bcl-2 |
MS1 peptide (4-8 μM) significantly increases mitochondrial membrane depolarization in encorafenib-pretreated DMBC11, DMBC12, DMBC21, DMBC28, and DMBC29 BRAFV600E melanoma cells, indicating altered cell dependence on anti-apoptotic proteins after encorafenib exposure[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1875102-20-7
-
Molecular Weight 2850.22
-
Formula C126H197N39O35S
-
Sequence
Ac-Arg-Pro-Glu-Ile-Trp-Met-Thr-Gln-Gly-Leu-Arg-Arg-Leu-Gly-Asp-Glu-Ile-Asn-Ala-Tyr-Tyr-Ala-Arg-NH2
-
Sequence Shortening
Ac-RPEIWMTQGLRRLGDEINAYYAR-NH2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz