pan-KRAS-IN-10
pan-KRAS-IN-10 (Compound 58) is an inhibitor for in human tumor mutated genes KRAS, which inhibits proliferation of KRAS mutated cells AsPC-1 (G12D mutant) and SW480 (G12V mutant) with IC50 of 0.7 and 0.24 nM, respectively.
For research use only. We do not sell to patients.
- Formula: C45H57N7O5S
- Molecular Weight:808.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 808.04
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Formula C45H57N7O5S
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SMILES
CO[C@@H](C)C(N=C1)=[C@@]([C@@]2=C(CC(C)(C)COC3=O)C4=CC(C5=CSC(C[C@H](NC([C@H]6[C@H](C)[C@@H]6C)=O)C(N7CCC[C@@H]3N7)=O)=N5)=CC=C4N2CC)C=C1C#CCN(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)