VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 (Compound 4a) is a dual VEGFR-2 and BRAF kinases inhibitor with IC50 values of 0.111, 0.089 and 0.071 µM against VEGFR-2, BRAFV600E and BRAFWT, respectively. VEGFR-2/BRAF-IN-2 induces apoptosis and arrests the cell cycle mainly in the G1 phase.
For research use only. We do not sell to patients.
- Formula: C26H21ClF3N5O3S2
- Molecular Weight:608.05
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
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Biological Activity
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BRAFWT 0.071 μM (IC50) |
BRafV600E 0.089 μM (IC50) |
VEGFR2 0.111 μM (IC50) |
Chemical Information
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Molecular Weight 608.05
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Formula C26H21ClF3N5O3S2
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SMILES
FC(F)(F)C1=CC=CC(NC(NNC(CSC2=NC3=C(C4=C(S3)CCCC4)C(N2C5=CC=C(C=C5)Cl)=O)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VEGFR-2/BRAF-IN-2 Related Classifications
HY-146492 Related Classifications
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