B-Raf IN 13
B-Raf IN 13 is a BRAF inhibitor with an IC50 of 3.55 nM in BRAF V600E enzyme assay. B-Raf IN 13 has anticaner effects (WO2020261156A1, Example 74).
For research use only. We do not sell to patients.
- CAS No.: 2573782-74-6
- Formula: C19H19ClFN3O4S
- Molecular Weight:439.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BRafV600E 3.55 nM (IC50) |
Chemical Information
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CAS No. 2573782-74-6
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Molecular Weight 439.89
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Formula C19H19ClFN3O4S
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SMILES
O=C1C2=C(C=CC(OC3=CC(F)=CC(NS(=O)(CCC)=O)=C3Cl)=C2C)N=CN1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B-Raf IN 13 Related Classifications
HY-150250 Related Classifications
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