THRA Protein, Human (His)
THRA Protein, Human (His) is the recombinant human-derived THRA protein, expressed by E. coli, with N-6*His tag.
- Species: Human
- Source: E. coli
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
THRA Protein, Human (His) is the recombinant human-derived THRA protein, expressed by E. coli, with N-6*His tag.
THRA is a nuclear hormone receptor that can function as either a repressor or activator of transcription. It serves as a high-affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Technical Parameters
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Species Human
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Source E. coli
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Tag N-6*His
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Accession
P10827-1 (M1-P490)
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Gene ID7067
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Protein Length
Full Length of Isoform-1
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Synonyms
THRA; AR7; Prev. ERBA1; V-ErbA-Related Protein 7; Prev. THRA1; C-ErbA Protooncogene; Prev. THRA2; EAR-7.1/EAR-7.2; NR1A1; C-ErbA-Alpha; Nuclear Receptor Subfamily 1 Group A Member 1; THRA3; THRalpha1; EAR-7; THRalpha2; EAR7; TRalpha1; Thyroid Hormone Rece
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AA Sequence
MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCSLKTSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNIPHFWPKLLMKEREVQSSILYKGAAAEGRPGGSLGVHPEGQQLLGMHVVQGPQVRQLEQQLGEAGSLQGPVLQHQSPKSPQQRLLELLHRSGILHARAVCGEDDSSEADSPSSSEEEPEVCEDLAGNAASP
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Predicted Molecular Mass
58.9 kDa
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Purity
≥ 85%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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