INCB126503
INCB126503 is an orally activeM, selective FGFR2/3 Inhibitor with IC50 values of 70 nM (FGFR1), 2.1 nM (FGFR2), 1.2 nM (FGFR3), 0.92 nM (FGFR3-V555L), 0.85 nM (FGFR3-V555M) and 64 nM (FGFR4). INCB126503 suppresses FGFR signaling in vivo without causing hyperphosphatemia and shows antitumor efficacy in xenograft models harboring FGFR3 genetic alterations.
For research use only. We do not sell to patients.
- CAS No.: 2640089-88-7
- Formula: C27H30N6O2
- Molecular Weight:470.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
CAS No. 2640089-88-7
-
Molecular Weight 470.57
-
Formula C27H30N6O2
-
SMILES
CC1=CC=CC(C2=NC3=C(NN=C3C4=CN=C(N5C[C@@](C[C@@H](O)C6)([H])N6CC5)C=C4)C=C2OC)=C1C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
INCB126503 Related Classifications
HY-174154 Related Classifications
Powered by Bioz