FXR agonist 14
FXR agonist 14 (Compound V15) is a partial, selective, orally active FXR agonist with an EC50 of 0.67 nM. FXR agonist 14 ameliorates pathological features in high-fat and high-sugar diet-induced MASH mice. FXR agonist 14 shows significant anti-cholestatic liver disease effects.
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- CAS No.: 3062988-46-6
- Formula: C30H33FN2O6S
- Molecular Weight:568.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 0.67 nM (FXR)[1]
Chemical Information
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CAS No. 3062988-46-6
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Molecular Weight 568.66
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Formula C30H33FN2O6S
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SMILES
O=S(C1=CC=CC=C1OC)(N(C2=CC=C(CC(N3CCC(C(OCC)=O)CC3)=O)C=C2)CC4=CC(F)=CC=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FXR agonist 14 Related Classifications
HY-180221 Related Classifications
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