3062988-46-6
3062988-46-6
Chemical Structure
FXR agonist 14
- CAS No.: 3062988-46-6
- Formula:C30H33FN2O6S
- Molecular Weight:568.66
InChIKey: GXATXBYYRNNKMW-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC=C1OC)(N(C2=CC=C(CC(N3CCC(C(OCC)=O)CC3)=O)C=C2)CC4=CC(F)=CC=C4)=O
Biological Activity: FXR agonist 14 (Compound V15) is a partial, selective, orally active FXR agonist with an EC50 of 0.67 nM. FXR agonist 14 ameliorates pathological features in high-fat and high-sugar diet-induced MASH mice. FXR agonist 14 shows significant anti-cholestatic liver disease effects[1].
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FXR agonist 14 | FXR agonist 14 (Compound V15) is a partial, selective, orally active FXR agonist with an EC50 of 0.67 nM. FXR agonist 14 ameliorates pathological features in high-fat and high-sugar diet-induced MASH mice. FXR agonist 14 shows significant anti-cholestatic liver disease effects. | |||||||||||||||||||||
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