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FGFR1 V561M Recombinant Human Active Protein Kinase

FGFR1 has been implicated in numerous cancer types including non-small cell lung cancer (NSCLC). FGFR1 is activated upon FGF binding to its extracellular domain, resulting in protein dimerization and transautophosphorylation of the intracellular tyrosine kinase domains. FGFR1 V561M gatekeeper mutation drives Fexagratinib (AZD4547) (HY-13330) resistance through STAT3 Activation and EMT. FGFR1 V561M Recombinant Human Active Protein Kinase is a recombinant FGFR1 V561M protein that can be used to study FGFR1 V561M-related functions.

For research use only. We do not sell to patients.

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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FGFR1 V561M Recombinant Human Active Protein Kinase Chemical Structure
    FGFR1 V561M Recombinant Human Active Protein Kinase Chemical Structure
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • FGFR1 V561M Recombinant Human Active Protein Kinase Chemical Structure
    FGFR1 V561M Recombinant Human Active Protein Kinase Chemical Structure
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  • FGFR1 V561M Recombinant Human Active Protein Kinase