Velmupressin
Velmupressin (c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2) is a potent, selective and short-acting peptidic V2 receptor (V2R) agonist with EC50s of 0.07 and 0.02 nM for hV2R and rV2R, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1647119-61-6
- Formula: C42H60ClN11O8S2
- Molecular Weight:946.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Vasopressin Receptor Isoforms
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Biological Activity
Description
IC50 & Target
EC50: 0.07 nM (hV2R), 0.02 nM (rV2R)[1]
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.02 nM
Compound: 38
|
Agonist activity at recombinant rat V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
Agonist activity at recombinant rat V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
|
[PMID: 31022340] |
| HEK293 | EC50 |
0.07 nM
Compound: 38
|
Agonist activity at recombinant human V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
Agonist activity at recombinant human V2 receptor expressed in HEK293 cells measured after 5 hrs by cAMP response element driven luciferase reporter gene assay
|
[PMID: 31022340] |
| HEK293 | EC50 |
110 nM
Compound: 38
|
Agonist activity at recombinant human V1B receptor expressed in HEK293 cells measured after 5 hrs by luciferase reporter gene assay
Agonist activity at recombinant human V1B receptor expressed in HEK293 cells measured after 5 hrs by luciferase reporter gene assay
|
[PMID: 31022340] |
Chemical Information
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CAS No. 1647119-61-6
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Molecular Weight 946.58
-
Formula C42H60ClN11O8S2
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Synonyms
c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)