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Telisotuzumab vedotin

(Synonyms: ABBV-399)
2 Cited Publications
고객리뷰

Based on 2 publication(s) in Google Scholar

Telisotuzumab vedotin (ABBV-399) (Teliso-V) is an anti-c-Met antibody-drug conjugate. Telisotuzumab vedotin consists of an anti-c-Met monoclonal antibody Telisotuzumab (ABT-700) (HY-P99391) and Monomethyl Auristatin E (HY-15162). Telisotuzumab vedotin exerts antitumor activity with acceptable toxicity in vivo. Telisotuzumab vedotin can be used for non-small cell lung cancer (NSCLC) research.

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  • Purity: 96.70%
  • CAS No.: 1714088-51-3
  • 분자량:145000 (average)
  • 보관:

    -80°C, protect from light

  • Telisotuzumab vedotin Chemical Structure
    Telisotuzumab vedotin Chemical Structure
  • Experimental Validation Results for Telisotuzumab vedotin
  • Experimental Validation Results for Telisotuzumab vedotin
  • Experimental Validation Results for Telisotuzumab vedotin
CAS No.: 1714088-51-3
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  • Telisotuzumab vedotin Chemical Structure
    Telisotuzumab vedotin Chemical Structure
    1/16
  • 1/16

    Telisotuzumab vedotin purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2026 Apr 21;7(4):102688. [Abstract]

    Customer Validation
     Comparison of tumor suppression between B6ADC and the combination of “marketed TROP2ADC (SG) and marketed c-MetADC (Telisotuzumab vedotin, 10 nmol/kg)” in SPC-A1 tumor-bearing mice (initial tumor volume: 600 mm3) (n = 5∼7/group).

  • 1/16

    Telisotuzumab vedotin purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2026 Apr 21;7(4):102688. [Abstract]

    Customer Validation
     Bioluminescence imaging of mice with orthotopic pancreatic tumors treated with B6ADC or the combination of "SG and Telisotuzumab vedotin (10 nmol/kg)" for 28 days (n = 4/group).

  • 1/16

    Telisotuzumab vedotin purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2026 Apr 21;7(4):102688. [Abstract]

    Customer Validation
     Survival curves of mice treated with B6ADC or SG+Telisotuzumab vedotin (10 nmol/kg). Survival analysis was performed using the Kaplan-Meier method, and statistical significance was determined by the log rank (Mantel-Cox) test.

  • Telisotuzumab vedotin