RET-IN-28
RET-IN-28 (Compound 16) is a RET (transmembrane receptor tyrosine protein kinase) inhibitor. RET-IN-28 inhibits the activity of the mutant RET enzyme (RET-V804M), and can be applied to cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2479961-45-8
- Formula: C26H29N9
- Molecular Weight:467.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
RET-IN-28 inhibits RET-V804M enzyme activity with a 92% inhibition rate (100 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2479961-45-8
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Molecular Weight 467.57
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Formula C26H29N9
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SMILES
CC(C=C1)=NC=C1CN(C(C2)C3)C2CN3C4=NC=C(C5=NC(NC6=NNC(C)=C6)=CC(C)=N5)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)