PROTAC Hemagglutinin Degrader-1
PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent PROTAC influenza hemagglutinin (HA) degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity.
(Pink: Influenza hemagglutinin (HA) ligand (HY-N0156); Blue: VHL ligand (HY-125845); Black: linker (HY-135804)).
For research use only. We do not sell to patients.
- CAS No.: 3031330-66-9
- Formula: C61H93N5O9S
- Molecular Weight:1072.48
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
More
Biological Activity
|
Influenza hemagglutinin (HA) |
VHL |
PROTAC Hemagglutinin Degrader-1 displays a moderate oral bioavailability of approximately 6.8%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3031330-66-9
-
Molecular Weight 1072.48
-
Formula C61H93N5O9S
-
SMILES
O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)[C@H](C(C)(C)C)NC(CCOCCOCCOCCNC([C@]45[C@](CC(C)(CC5)C)([H])C6=CC[C@@]([C@@]7([C@@](C(C)([C@H](CC7)O)C)([H])CC8)C)([H])[C@]8(C)[C@@]6(CC4)C)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)