Anticancer agent 223
Anticancer agent 223 (Compound V-d) is an anticancer agent that triggers cell death through caspase-dependent and caspase-independent mechanisms. Anticancer agent 223 inhibits tumor spheroid formation and resensitizes cisplatin (HY-17394)-resistant A2780 cells to cisplatin (HY-17394) treatment.
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- No. CAS: 1328150-75-9
- Fòrmula: C20H19ClN4O
- Peso molecular:366.84
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
5.68 μM
Compound: V-d
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Antiproliferative activity against human A2780 cells assessed as cell viability incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human A2780 cells assessed as cell viability incubated for 72 hrs by CCK8 assay
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[PMID: 38754563] |
| HK-2 | IC50 |
>50 μM
Compound: V-d
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Cytotoxicity against HK-2 cells
Cytotoxicity against HK-2 cells
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[PMID: 38754563] |
Chemical Information
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No. CAS 1328150-75-9
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Peso molecular 366.84
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Fòrmula C20H19ClN4O
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SMILES
ClC1=CC=C(NC(C2CCN(C3=NC=NC4=C3C=CC=C4)CC2)=O)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 223 Related Classifications
HY-161661 Related Classifications
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