Eg5 Inhibitor V, trans-24
Based on 1 Customer Validation
Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer.
For research use only. We do not sell to patients.
- Purity: 98.18%
- CAS No.: 869304-55-2
- Formula: C26H21N3O3
- Molecular Weight:423.46
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Kinesin Isoforms
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Biological Activity
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Eg5 0.65 μM (IC50) |
Chemical Information
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CAS No. 869304-55-2
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Appearance Solid
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Molecular Weight 423.46
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Formula C26H21N3O3
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Color White to light yellow
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SMILES
O=C([C@]1([H])CC2=C([C@@H](C3=CC=CC(O)=C3)N14)NC5=C2C=CC=C5)N(CC6=CC=CC=C6)C4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 45 mg/mL (106.27 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3615 mL | 11.8075 mL | 23.6150 mL | 59.0375 mL |
| 5 mM | 0.4723 mL | 2.3615 mL | 4.7230 mL | 11.8075 mL | |
| 10 mM | 0.2361 mL | 1.1807 mL | 2.3615 mL | 5.9037 mL | |
| 15 mM | 0.1574 mL | 0.7872 mL | 1.5743 mL | 3.9358 mL | |
| 20 mM | 0.1181 mL | 0.5904 mL | 1.1807 mL | 2.9519 mL | |
| 25 mM | 0.0945 mL | 0.4723 mL | 0.9446 mL | 2.3615 mL | |
| 30 mM | 0.0787 mL | 0.3936 mL | 0.7872 mL | 1.9679 mL | |
| 40 mM | 0.0590 mL | 0.2952 mL | 0.5904 mL | 1.4759 mL | |
| 50 mM | 0.0472 mL | 0.2361 mL | 0.4723 mL | 1.1807 mL | |
| 60 mM | 0.0394 mL | 0.1968 mL | 0.3936 mL | 0.9840 mL | |
| 80 mM | 0.0295 mL | 0.1476 mL | 0.2952 mL | 0.7380 mL | |
| 100 mM | 0.0236 mL | 0.1181 mL | 0.2361 mL | 0.5904 mL |