2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Cytoskeleton
  4. Kinesin
  5. Kinesin Inhibitors

Kinesin Inhibitors

Kinesin-5/Eg5/KSP

Kinesin-6

Kinesin-7/CENP-E

Kinesin-12

Kinesin-14

Kinesin-13

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Kinesin Inhibitors, Activators & Degraders
Product Name Kinesin-5/Eg5/KSP Kinesin-6 Kinesin-7/CENP-E Kinesin-12 Kinesin-14 Kinesin-13 Purity
Ispinesib
KSP, Ki app: 1.7 nM
          99.62%
Monastrol
Eg5, IC50: 14 μM
          99.89%
S-Trityl-L-cysteine
Eg5
          99.53%
GSK-923295    
CENP-E, Ki: 1.6 nM (Canine CENP-E)
      99.95%
LP-6 TFA
Eg5
         
CCT368772
Eg5, IC50: >200 μM
         
Filanesib
KSP, IC50: 6 nM
          99.59%
AZ82        
HSET/KIFC1, IC50: 300 nM
HSET/KIFC1, Ki: 43 nM
  99.86%
Paprotrain  
MKLP-2, IC50: 1.35 μM
        99.85%
SB-743921 hydrochloride
Eg5, Ki: 0.1 nM
          99.76%
Dimethylenastron
Eg5, IC50: 200 nM
          98.27%
Kif15-IN-1      
KIF15
    99.63%
UMK57          
Kif2c/MCAK
99.51%
CW-069        
HSET, IC50: 75 μM
  99.37%
MK-0731
KSP, IC50: 2.2 nM
          99.85%
Litronesib
Eg5
          99.59%
EMD534085
Kinesin-5, IC50: 8 nM
          99.55%
PVZB1194
Eg5
          99.64%
ARQ 621
Eg5
          ≥99.0%
PF-2771    
CENP-E, IC50: 16.1 nM
      99.66%
Syntelin    
CENP-E, IC50: 160 nM
      98.25%
K858 (Racemic)
Eg5, IC50: 1.3 μM
          99.83%
Kif15-IN-2      
KIF15
    98.38%
LP-6
Eg5
         
Eg5 Inhibitor V, trans-24
Eg5, IC50: 0.65 μM
          98.18%
DHTP          
Kif2a, IC50: 1.2 μM
Kif2c/MCAK, IC50: 4.6 μM
NVP-BQS481
Eg5, : <0.5 nM
         
CENP-E-IN-2    
CENP-E
     
Terpendole E
Eg5
         
Ispinesib mesylate
KSP, Ki app: 1.7 nM
         
PROTAC KSP degrader 1
KSP, DC50: 114.8 nM
         
CCT369834        
HSET, IC50: 39 nM
 
CENP-E-IN-3    
CENP-E
     
NSC-80141
Kinesin-5