pan-KRAS-IN-13
pan-KRAS-IN-13 (compound 2) is a potent inhibitor of KRAS, with IC50s of 2.75 nM and 2.89 nM for G12D and G12V, respectively
For research use only. We do not sell to patients.
- CAS No.: 3033637-76-9
- Formula: C33H31F3N6O3
- Molecular Weight:616.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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KRas G12D 2.75 nM (IC50) |
KRas G12V 2.89 nM (IC50) |
Chemical Information
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CAS No. 3033637-76-9
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Molecular Weight 616.63
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Formula C33H31F3N6O3
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SMILES
FC1=C(C#C)C2=C(C3=NC(OCC4)=C(C(N5[C@@H]4CNCC5)=NC(OC[C@]6(C[C@@H](F)C7)N7CCC6)=N8)C8=C3F)C=C(O)C=C2C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)