1. Apoptosis
  2. Bcl-2 Family
  3. S65487

S65487 (Synonyms: VOB560)

Cat. No.: HY-138697
Handling Instructions

S65487 (VOB560) is a potent and selective Bcl-2 inhibitor. S65487 has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 has anticaner activities.

For research use only. We do not sell to patients.

S65487 Chemical Structure

S65487 Chemical Structure

CAS No. : 1644600-79-2

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Description

S65487 (VOB560) is a potent and selective Bcl-2 inhibitor. S65487 has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 has anticaner activities[1][2].

In Vivo

S65487 (VOB560; Compound A; i.v.; once a week; over two weeks) treatment decreases the tumor growth in RS4;ll grafted female SCID mice, and does not affect body weight[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

717.26

Formula

C₄₁H₄₁ClN₆O₄

CAS No.
SMILES

O=C(C1=C(C)N(C)C(C2=C(C=CC(Cl)=C2)C(N3[[email protected]@H](CC4=CC=CC=C4C3)CN5CCOCC5)=O)=C1)N(C6=CC=C(C=C6)O)C7=C(C)N(C)C(C#N)=C7

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

S65487VOB560S 65487S-65487VOB 560VOB-560Bcl-2 FamilyanticanerInhibitorinhibitorinhibit

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