KRAS-IN-48
KRAS-IN-48 (Compound 1-01) is a KRAS mutant inhibitor, with Kd values of 2.58 nM and 5.49 μM for KRAS-G12D and KRAS-G12V, respectively. KRAS-IN-48 can be used in the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3074833-87-4
- Formula: C37H41F2N7O7
- Molecular Weight:733.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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KRas G12D 2.58 nM (Kd) |
KRas G12V 5.49 μM (Kd) |
Chemical Information
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CAS No. 3074833-87-4
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Molecular Weight 733.76
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Formula C37H41F2N7O7
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SMILES
OC=O.F[C@H](C1)CN(CCC2)[C@]12COC3=NC(N4CC5NC(CC5)C4)=C6N(C7CCC7)C(OC8=CC(O)=CC9=C8C(C#C)=C(F)C=C9)=NC6=N3.OC=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)