HIV-1 inhibitor-29
HIV-1 inhibitor-29 (compound 14d2) is a potent HIV-1 inhibitor with an EC50 of 2.18 μM for HIV-1 IIIB. HIV-1 inhibitor-29 has high anti-resistance profile toward F227L/V106A strain (EC50 = 0.974 μM), and exhibits low cytotoxicity in MT-4 cells (CC50 = 211 μM). HIV-1 inhibitor-29 can be used for researching AIDS.
For research use only. We do not sell to patients.
- CAS No.: 2642217-95-4
- Formula: C30H36N6O5
- Molecular Weight:560.64
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
HIV (IIIB) 2.18 μM (EC50) |
HIV-1 (F227L/V106A) 0.974 μM (EC50) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
211 μM
Compound: 14d2
|
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
Cytotoxicity against human MT4 cells assessed as reduction in cell viability incubated for 5 days by MTT assay
|
[PMID: 32977301] |
Chemical Information
-
CAS No. 2642217-95-4
-
Molecular Weight 560.64
-
Formula C30H36N6O5
-
SMILES
COC1=CC2=NC(NC3CCN(CC3)CC(N4CCOCC4)=O)=NC(OC5=C(C=C(C=C5C)C#N)C)=C2C=C1OC
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)