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  3. Qstatin

Qstatin 

Cat. No.: HY-124796 Purity: 99.56%
Handling Instructions

QStatin is a novel, potent, and selective Vibrio quorum sensing (QS) inhibitor, shows pan-QS inhibitor activity in diverse Vibrio species. QStatin attenuates representative QS-regulated phenotypes in various Vibrio speciesbinds tightly to a putative ligand-binding pocket in SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity. QStatin may be a sustainable antivibriosis agent useful in aquacultures.

For research use only. We do not sell to patients.

Qstatin Chemical Structure

Qstatin Chemical Structure

CAS No. : 902688-24-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 100 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
50 mg USD 400 In-stock
Estimated Time of Arrival: December 31
100 mg USD 650 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

QStatin is a novel, potent, and selective Vibrio quorum sensing (QS) inhibitor, shows pan-QS inhibitor activity in diverse Vibrio species. QStatin attenuates representative QS-regulated phenotypes in various Vibrio speciesbinds tightly to a putative ligand-binding pocket in SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity. QStatin may be a sustainable antivibriosis agent useful in aquacultures[1].

Molecular Weight

293.16

Formula

C₇H₅BrN₂O₂S₂

CAS No.

902688-24-8

SMILES

O=S(N1N=CC=C1)(C2=CC=C(Br)S2)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (284.25 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4111 mL 17.0555 mL 34.1111 mL
5 mM 0.6822 mL 3.4111 mL 6.8222 mL
10 mM 0.3411 mL 1.7056 mL 3.4111 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (7.10 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (7.10 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (7.10 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.56%

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Qstatin
Cat. No.:
HY-124796
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