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Cat. No.: HY-159758

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EcDHFR/FKBP12 F36V binder-1

EcDHFR/FKBP12 F36V binder-1 (compound 1) is a bifunctional molecule that combines the Escherichia coli dihydrofolate reductase domain (EcDHFR) with the FKBP12 F36V domain.

For research use only. We do not sell to patients.

CAS No.: 3080922-95-5
Formula: C₅₄H₆₈N₆O₁₃
Molecular Weight:1009.15

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

EcDHFR/FKBP12 F36V binder-1 Chemical Structure

CAS No.: 3080922-95-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

EcDHFR/FKBP12 F36V binder-1 (compound 1) is a bifunctional molecule that combines the Escherichia coli dihydrofolate reductase domain (EcDHFR) with the FKBP12 F36V domain^[1].

Chemical Information

CAS No. 3080922-95-5
Molecular Weight 1009.15
Formula C₅₄H₆₈N₆O₁₃
SMILES

CC[C@H](C(N1CCCC[C@H]1C(O[C@H](CCC2=CC(OC)=C(OC)C=C2)C3=CC(OCC(NCCCOC4=C(OC)C=C(CC5=CN=C(N)N=C5N)C=C4OC)=O)=CC=C3)=O)=O)C6=CC(OC)=C(OC)C(OC)=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ng CSC, et al. Targeted protein relocalization via protein transport coupling. Nature. 2024 Sep;633(8031):941-951. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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