JAK2-IN-10
Based on 1 Customer Validation
JAK2-IN-10 is a selective JAK2 V617F inhibitor with an IC50 value of ≤10 nM. JAK2-IN-10 can be used for the research of myeloproliferative neoplasms and other related diseases.
For research use only. We do not sell to patients.
- Purity: 97.97%
- CAS No.: 3035735-18-0
- Formula: C33H33D3FN9O2
- Molecular Weight:612.71
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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JAK2-V617F ≤10 nM (IC50) |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3035735-18-0
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Appearance Solid
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Molecular Weight 612.71
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Formula C33H33D3FN9O2
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Color White to off-white
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SMILES
O=C(N1C)N([C@@H]2CC[C@@](NC(C3CC3)=O)(C)CC2)C4=C1C=NC5=C4C(C6=CC(C=NN7C([2H])([2H])[2H])=C7C=C6)=C(C8=CN(CC)N=C8F)N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (40.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (283 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.6321 mL | 8.1605 mL | 16.3209 mL | 40.8023 mL |
| 5 mM | 0.3264 mL | 1.6321 mL | 3.2642 mL | 8.1605 mL | |
| 10 mM | 0.1632 mL | 0.8160 mL | 1.6321 mL | 4.0802 mL | |
| 15 mM | 0.1088 mL | 0.5440 mL | 1.0881 mL | 2.7202 mL | |
| 20 mM | 0.0816 mL | 0.4080 mL | 0.8160 mL | 2.0401 mL | |
| 25 mM | 0.0653 mL | 0.3264 mL | 0.6528 mL | 1.6321 mL | |
| 30 mM | 0.0544 mL | 0.2720 mL | 0.5440 mL | 1.3601 mL | |
| 40 mM | 0.0408 mL | 0.2040 mL | 0.4080 mL | 1.0201 mL |
JAK2-IN-10 Related Classifications
HY-161684 Related Classifications
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