JAK2-IN-10
Based on 1 Customer Validation
JAK2-IN-10 is a selective JAK2 V617F inhibitor with an IC50 value of ≤10 nM. JAK2-IN-10 can be used for the research of myeloproliferative neoplasms and other related diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.97%
- CAS 番号: 3035735-18-0
- 分子式: C33H33D3FN9O2
- 分子量:612.71
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
JAK2-V617F ≤10 nM (IC50) |
体外実験
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 3035735-18-0
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性状 Solid
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分子量 612.71
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分子式 C33H33D3FN9O2
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Color White to off-white
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SMILES
O=C(N1C)N([C@@H]2CC[C@@](NC(C3CC3)=O)(C)CC2)C4=C1C=NC5=C4C(C6=CC(C=NN7C([2H])([2H])[2H])=C7C=C6)=C(C8=CN(CC)N=C8F)N5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (40.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (283 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.6321 mL | 8.1605 mL | 16.3209 mL | 40.8023 mL |
| 5 mM | 0.3264 mL | 1.6321 mL | 3.2642 mL | 8.1605 mL | |
| 10 mM | 0.1632 mL | 0.8160 mL | 1.6321 mL | 4.0802 mL | |
| 15 mM | 0.1088 mL | 0.5440 mL | 1.0881 mL | 2.7202 mL | |
| 20 mM | 0.0816 mL | 0.4080 mL | 0.8160 mL | 2.0401 mL | |
| 25 mM | 0.0653 mL | 0.3264 mL | 0.6528 mL | 1.6321 mL | |
| 30 mM | 0.0544 mL | 0.2720 mL | 0.5440 mL | 1.3601 mL | |
| 40 mM | 0.0408 mL | 0.2040 mL | 0.4080 mL | 1.0201 mL |
JAK2-IN-10 関連分類
HY-161684 関連分類
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