1. MAPK/ERK Pathway
  2. Raf
  3. BRAF V600E/CRAF-IN-2

BRAF V600E/CRAF-IN-2 

Cat. No.: HY-146443
Handling Instructions

BRAF V600E/CRAF-IN-2 (Compound 9c) is a potent inhibitor of BRAF V600E/CRAF with IC50s of 0.888 and 0.229 μM, respectively. BRAF V600E/CRAF-IN-2 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-2 has the potential for the research of cancer diseases.

For research use only. We do not sell to patients.

BRAF V600E/CRAF-IN-2 Chemical Structure

BRAF V600E/CRAF-IN-2 Chemical Structure

CAS No. : 2499499-62-4

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Description

BRAF V600E/CRAF-IN-2 (Compound 9c) is a potent inhibitor of BRAF V600E/CRAF with IC50s of 0.888 and 0.229 μM, respectively. BRAF V600E/CRAF-IN-2 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-2 has the potential for the research of cancer diseases[1].

Molecular Weight

549.59

Formula

C30H30F3N5O2

CAS No.
SMILES

CCN1CCN(CC1)C2=CC(C(F)(F)F)=CC(C(NC3=CC=CC(NC4=NC5=CC=CC(OC)=C5C=C4)=C3)=O)=C2

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BRAF V600E/CRAF-IN-2
Cat. No.:
HY-146443
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