1. Anti-infection
  2. Bacterial
  3. Tunicamycin V

Tunicamycin V (Synonyms: Tunicamycin A)

Cat. No.: HY-N8395 Purity: ≥95.0%

Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties.

For research use only. We do not sell to patients.

Tunicamycin V Chemical Structure

Tunicamycin V Chemical Structure

CAS No. : 66054-36-2

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Estimated Time of Arrival: December 31
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Description

Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties[1][2].

IC50 & Target

IC50: 0.35 μM (phospho-N-acetylmuramyl-pentapeptide transferase (MraY))[1]

In Vitro

Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

830.92

Formula

C₃₈H₆₂N₄O₁₆

CAS No.

66054-36-2

SMILES
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References

Purity: ≥95.0%

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Keywords:

Tunicamycin VTunicamycin ABacterialMraYantibacterialnucleosideInhibitorinhibitorinhibit

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Tunicamycin V
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