1. Anti-infection
  2. Reverse Transcriptase
    HIV
  3. Dexelvucitabine

Dexelvucitabine (Synonyms: Reverset; d-d4FC)

Cat. No.: HY-14920
Handling Instructions

Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful drug against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent.

For research use only. We do not sell to patients.

Dexelvucitabine Chemical Structure

Dexelvucitabine Chemical Structure

CAS No. : 134379-77-4

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5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 480 In-stock
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25 mg USD 970 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1550 In-stock
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100 mg USD 2450 In-stock
Estimated Time of Arrival: December 31
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Description

Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful drug against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent[1].

IC50 & Target[1]

HIV-1

 

In Vivo

Dexelvucitabine (Reverset; d-d4FC; 33.3 mg/kg by i.v. or p.o.) has distribution and elimination half-lives (t1/2α and t1/2β, respectively) of 0.7 and 3.6 h in monkeys, respectively. The Cmax ranges from 21.1 to 47.5 μM[2].
Dexelvucitabine has a favorable pharmacokinetic profile with a long half-life (4.71 and 10.75 h after administration by the intravenous [i.v.] and oral [p.o.] routes, respectively) in woodchucks[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

227.19

Formula

C9H10FN3O3

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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Dexelvucitabine
Cat. No.:
HY-14920
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