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Cat. No.: HY-N7202

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Angulatin A

Name: Angulatin A
Brand: MedChemExpress
SKU: HY-N7202
Price: 312.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: (-)-Angulatin A; Celangulin V)

Angulatin A (Celangulin V) is a natural product that can be found in Celastrus angulatus. Angulatin A is a novel botanical insecticide with a toxic activity against agricultural insect pests. Angulatin A can bind to subunits a, H, and B of the vacuolar ATPase (V-ATPase) in the midgut epithelial cells of insects.

For research use only. We do not sell to patients.

CAS No.: 139979-81-0
Formula: C₃₄H₄₆O₁₃
Molecular Weight:662.72

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (300 KB)

Angulatin A Chemical Structure

CAS No.: 139979-81-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Angulatin A (Celangulin V) is a natural product that can be found in Celastrus angulatus^[1]. Angulatin A is a novel botanical insecticide with a toxic activity against agricultural insect pests. Angulatin A can bind to subunits a, H, and B of the vacuolar ATPase (V-ATPase) in the midgut epithelial cells of insects^[2].

Chemical Information

CAS No. 139979-81-0
Appearance Solid
Molecular Weight 662.72
Formula C₃₄H₄₆O₁₃
Color White to off-white
SMILES

CC(C)C(OC[C@]12[C@H](OC(C3=CC=CC=C3)=O)[C@@H](OC(C(C)C)=O)[C@@]([C@H]4O)([H])C(C)(C)O[C@@]14[C@@](C)(O)C[C@H](OC(C)=O)[C@@H]2OC(C)=O)=O
Synonyms

(-)-Angulatin A; Celangulin V
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (300 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hai-Yan Zhang, et al. Four new sesquiterpene polyol esters from Celastrus angulatus, Phytochemistry Letters. 2014,7, 101-106.

[2]. Ding L, Guo Z, Xu H, Li T, Wang Y, Tao H. The Inhibitory Effect of Celangulin V on the ATP Hydrolytic Activity of the Complex of V-ATPase Subunits A and B in the Midgut of Mythimna separata. Toxins (Basel). 2019 Feb 22;11(2):130.

[3]. Wang Y, Zhang J, Feng M, Wu W, Hu Z. Insight into the Mode of Action of Celangulin V on the Transmembrane Potential of Midgut Cells in Lepidopteran Larvae. Toxins (Basel). 2017 Dec 6;9(12):393.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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