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Click Chemistry:	PROTAC Synthesis (10) Azide (9) Alkynes (5)

1500

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

121

Peptides

MCE Kits

Inhibitory Antibodies

169

Natural
Products

182

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113344

16α-Hydroxyestrone 1 Publications Verification 16αOHE	Endogenous Metabolite	Metabolic Disease
16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease .

HY-106420

16,16-Dimethyl prostaglandin E2 16,16-dimethyl PGE2	Prostaglandin Receptor	Inflammation/Immunology
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway .

HY-114751

16,16-Dimethylprostaglandin E1 16,16-dimethyl-PGE1	Others	Cardiovascular Disease
16,16-Dimethylprostaglandin E1 (16,16-dimethyl-PGE1) is a PGE1 (HY-B0131) analog, induces bronchoconstrict and vascular smooth muscle contractions and suppresses the indomethacin induced cellular elongation .

HY-146891S

16:0-16:0 PC-d31

Isotope-Labeled Compounds Others

16:0-16:0 PC-d₃₁ is deuterium labeled 16:0-16:0 PC.

16:0-16:0 PC-d31	Isotope-Labeled Compounds	Others
16:0-16:0 PC-d₃₁ is deuterium labeled 16:0-16:0 PC.

HY-137270

16,16-Dimethyl PGA2 16,16-Dimethyl prostaglandin A2; Di-M-PGA2	Endogenous Metabolite	Endocrinology Cancer
16,16-Dimethyl PGA2 is an orally active prostaglandin analog with a prolonged in vivo half-life. 16,16-Dimethyl PGA2 can be used to study hypertension .

HY-N9725

16-Hydroxycleroda-3,13-dien-15,16-olide 16ξ-Hydroxycleroda-3,13-dien-15,16-olide	Dipeptidyl Peptidase	Metabolic Disease
16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy .

HY-N1599

16-Epivoacarpine

16-epi-Voacarpine
Others Others

16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .

16-Epivoacarpine 16-epi-Voacarpine	Others	Others
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .

HY-137492

16,16-Dimethyl-PGE2-4-(4-acetamidobenzamido)phenyl ester	Others	Metabolic Disease
16,16-Dimethyl-PGE2-4-(4-acetamidobenzamido)phenyl ester is a derivative of 16,16-Dimethyl-PGE2 (HY-106420). 16,16-Dimethyl-PGE2-4-(4-acetamidobenzamido)phenyl ester is a prodrug for 16,16-Dimethyl-PGE2 .

HY-128378

16-Dehydroprogesterone

Endogenous Metabolite Endocrinology

16-Dehydroprogesterone is a steroidal progestin.
HY-N2431

16-Methoxystrychnine

Others Others

16-Methoxystrychnine is a alkaloid .
HY-146914S

16:0-18:0-16:0 TG-d5

Isotope-Labeled Compounds Others

16:0-18:0-16:0 TG-d₅ is deuterium labeled 16:0-18:0-16:0 TG.

16-Dehydroprogesterone	Endogenous Metabolite	Endocrinology
16-Dehydroprogesterone is a steroidal progestin.

16-Methoxystrychnine	Others	Others
16-Methoxystrychnine is a alkaloid .

16:0-18:0-16:0 TG-d5	Isotope-Labeled Compounds	Others
16:0-18:0-16:0 TG-d₅ is deuterium labeled 16:0-18:0-16:0 TG.

HY-130046

16-Epiestriol 16-epi-Estriol; 16β,17β-Estriol	Bacterial	Infection Inflammation/Immunology
16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects[1][2][3].

HY-118670A

16(R)-Iloprost

Others Cardiovascular Disease

16(R)-Iloprost is a stereoisomer of Iloprost. 16(R)-Iloprost inhibited platelet aggregation with IC₅₀ value of 65 nM .

16(R)-Iloprost	Others	Cardiovascular Disease
16(R)-Iloprost is a stereoisomer of Iloprost. 16(R)-Iloprost inhibited platelet aggregation with IC₅₀ value of 65 nM .

HY-116444A

16-HETE	Na+/K+ ATPase	Cardiovascular Disease Inflammation/Immunology
16-HETE is arachidonic acid metabolite through subterminal hydroxylation by cytochrome P-450. 16-HETE exhibits vasodilatory and PMN inhibitory effects and serves as biomarker for early stages of non-alcoholic fatty liver disease .

HY-113031S

16α-Hydroxydehydroepiandrosterone-d5 16α-hydroxy-DHEA-d₅; 16α-OH-DHEA-d₅	Isotope-Labeled Compounds Endogenous Metabolite	Others
16α-Hydroxydehydroepiandrosterone-d₅ (16α-Hydroxy-DHEA-d₅) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone[1].

HY-146930S

16:1 SM (d18:1/16:1)-d9

Isotope-Labeled Compounds Others

16:1 SM (d18:1/16:1)-d₉ is deuterium labeled 16:1 SM (d18:1/16:1).
HY-N12542

16-Anhydrodeacetylnerigoside

Others Others

16-Anhydrodeacetylnerigoside (compound 4) is a steroid that can be found in Nerium indicum .

16:1 SM (d18:1/16:1)-d9	Isotope-Labeled Compounds	Others
16:1 SM (d18:1/16:1)-d₉ is deuterium labeled 16:1 SM (d18:1/16:1).

16-Anhydrodeacetylnerigoside	Others	Others
16-Anhydrodeacetylnerigoside (compound 4) is a steroid that can be found in Nerium indicum .

HY-118670

16(S)-Iloprost	Others	Cardiovascular Disease
16(S)-Iloprost is a stereoisomer of Iloprost. 16(S)-Iloprost inhibited platelet aggregation with IC₅₀ value of 3.5 nM, and balanced binding with platelet membrane receptors K_d value of 13.4 nM .

HY-N11513

16-Epipyromesaconitine

Others Others

16-Epipyromesaconitine is a natural product that can be obtained by the pyrolysis of Mesaconitine (HY-N0724) .
HY-163165S

16:0-19:2-16:0 TG-d5

Isotope-Labeled Compounds Metabolic Disease

16:0-19:2-16:0 TG-d₅ is the deuterium labeled triacylglycerols.

16-Epipyromesaconitine	Others	Others
16-Epipyromesaconitine is a natural product that can be obtained by the pyrolysis of Mesaconitine (HY-N0724) .

16:0-19:2-16:0 TG-d5	Isotope-Labeled Compounds	Metabolic Disease
16:0-19:2-16:0 TG-d₅ is the deuterium labeled triacylglycerols.

HY-116758

16,16-Dimethyl prostaglandin A1 di-Me-PGA1	DNA/RNA Synthesis HIV HSV	Infection Cancer
16,16-Dimethyl prostaglandin A1 (di-Me-PGA1) is a prostaglandin analog that can inhibit DNA synthesis in Lewis lung carcinoma and B 16 amelanotic melanoma cells. 16,16-Dimethyl prostaglandin A1 also inhibits viral replication in both HSV and HIV-1 infection systems .

HY-15278A

(16R)-Epothilone D (16R)-KOS 862	Others	Infection Cancer
(16R)-Epothilone D is the isomer of Epothilone D (HY-15278), and can be used as an experimental control. Epothilone D (KOS 862) is a potent microtubule stabilizer.

HY-116056

16-O-Methylcafestol

Others Others

16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans .
HY-120894

16(R)-HETE

Endogenous Metabolite Others

16(R)-HETE, a metabolite of the cytochrome P450 branch of the arachidonate cascade, is a vasodilator .
HY-N2992

16α-Hydroxytrametenolic acid

RAR/RXR Cancer

16α-Hydroxytrametenolic acid, a natural triterpene, is a potential retinoid X receptor (RXR) selective agonist .
HY-N0959

(16R)-E-Isositsirikine

16(R)-19,20-E-Isositsirikine

(16R)-E-Isositsirikine is an indole alkaloid compound from Catharanthus roseus Tissue Cultures IV1 .
HY-116444

16(S)-HETE

Others Neurological Disease

16(S)-HETE is an endogenous inhibitor of neutrophil activity and can be used in the study of acute ischemic brain injury .

16-O-Methylcafestol	Others	Others
16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans .

16(R)-HETE	Endogenous Metabolite	Others
16(R)-HETE, a metabolite of the cytochrome P450 branch of the arachidonate cascade, is a vasodilator .

16α-Hydroxytrametenolic acid	RAR/RXR	Cancer
16α-Hydroxytrametenolic acid, a natural triterpene, is a potential retinoid X receptor (RXR) selective agonist .

(16R)-E-Isositsirikine 16(R)-19,20-E-Isositsirikine
(16R)-E-Isositsirikine is an indole alkaloid compound from Catharanthus roseus Tissue Cultures IV1 .

16(S)-HETE	Others	Neurological Disease
16(S)-HETE is an endogenous inhibitor of neutrophil activity and can be used in the study of acute ischemic brain injury .

HY-144016

16:0 EPC chloride	Liposome	Others
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery .

HY-N1603

16-o-Acetyldarutigenol

Others Others

16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
HY-143695

16:0 TAP

Liposome Others

16:0 TAP is a lipid product. 16:0 TAP can be used for the preparation of giant unilamellar vesicles to deliver agents .

16-o-Acetyldarutigenol	Others	Others
16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .

16:0 TAP	Liposome	Others
16:0 TAP is a lipid product. 16:0 TAP can be used for the preparation of giant unilamellar vesicles to deliver agents .

HY-N8971

Bauer-7-ene-3β,16α-diol 16α-Hydroxybauerenol	Bacterial	Infection
Bauer-7-ene-3β,16α-diol, a triterpenoid, is a natural product that can be isolated from dried flower buds of Tussilago farfara L. or Petasites tricholobus (Compositae). Bauer-7-ene-3β,16α-diol shows medium antibacterial activity against E. coli .

HY-N7950

16-Oxoalisol A	Others	Metabolic Disease
16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases .

HY-N1602

16-Nor-15-oxodehydroabietic acid

Others Others

16-Nor-15-oxodehydroabietic acid (compound 32) is a compound isolated from the root bark of Pinus massoniana .
HY-N9011

16-Oxo-11-anhydroalisol A

Others Inflammation/Immunology

16-Oxo-11-anhydroalisol A is a triterpenoid from Alisma orientale .

16-Nor-15-oxodehydroabietic acid	Others	Others
16-Nor-15-oxodehydroabietic acid (compound 32) is a compound isolated from the root bark of Pinus massoniana .

16-Oxo-11-anhydroalisol A	Others	Inflammation/Immunology
16-Oxo-11-anhydroalisol A is a triterpenoid from Alisma orientale .

HY-N2990

16α-Hydroxydehydrotrametenolic acid 3β,16α-Dihydroxylanosta-7,9(11),24-trien-21-oic acid	Others	Inflammation/Immunology
16α-Hydroxydehydrotrametenolic acid is a triterpene Acid in fermented mycelia of edible fungus Poria cocos .

HY-N1600

16(R/S)-Hydroxy-3,13Z-kolavadien-15,16-olide-2-one	Others	Others
16(R/S)-Hydroxy-3,13Z-kolavadien-15,16-olide-2-one (compound 9) is a diterpene compound isolated from the unripe fruits of Polyalthia longifolia var. pendula .

HY-137141

16-Keto Aspergillimide

SB202327
Parasite Infection

16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .
HY-N11486

16β-Hydroperoxyalisol B 23-acetate

Others Others

16β-Hydroperoxyalisol B 23-acetate is a natural product that can be isolated from Alisma orientale .
HY-N0958

(16R)-Dihydrositsirikine

19,20-Dihydroisositsirikine
Others Others

(16R)-Dihydrositsirikine (19,20-Dihydroisositsirikine) is a natural alkaloid compound .
HY-146779S

16:1 Cholesteryl ester-d7

Isotope-Labeled Compounds Others

16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.
HY-146926S

16:0 Coenzyme A-d4

Isotope-Labeled Compounds Others

16:0 Coenzyme A-d₄ is deuterium labeled 16:0 Coenzyme A.
HY-142798S

16-Keto 17β-Estradiol-d5 (Major)

Isotope-Labeled Compounds Others

16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].
HY-N1595

16-Acetoxy-7-O-acetylhorminone

16-Acetoxy-7-O-acetylhorminone is a compound isolated from the leaves of Rabdosia lophanthoides var. gerardiana .
HY-146918S

16:0 (Rac)-PtdEG-d71

Isotope-Labeled Compounds Others

16:0 (Rac)-PtdEG-d₇₁ is deuterium labeled 16:0 (Rac)-PtdEG.
HY-146924S

16:0 (Rac)-PC-d80

Isotope-Labeled Compounds Others

16:0 (Rac)-PC-d₈₀ is deuterium labeled 16:0 (Rac)-PC.
HY-N3939

Gelsempervine A

16-epi-Nb-Methylvoacarpine
Others Others

Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .

16-Keto Aspergillimide SB202327	Parasite	Infection
16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .

16β-Hydroperoxyalisol B 23-acetate	Others	Others
16β-Hydroperoxyalisol B 23-acetate is a natural product that can be isolated from Alisma orientale .

(16R)-Dihydrositsirikine 19,20-Dihydroisositsirikine	Others	Others
(16R)-Dihydrositsirikine (19,20-Dihydroisositsirikine) is a natural alkaloid compound .

16:1 Cholesteryl ester-d7	Isotope-Labeled Compounds	Others
16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.

16:0 Coenzyme A-d4	Isotope-Labeled Compounds	Others
16:0 Coenzyme A-d₄ is deuterium labeled 16:0 Coenzyme A.

16-Keto 17β-Estradiol-d5 (Major)	Isotope-Labeled Compounds	Others
16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].

16-Acetoxy-7-O-acetylhorminone
16-Acetoxy-7-O-acetylhorminone is a compound isolated from the leaves of Rabdosia lophanthoides var. gerardiana .

16:0 (Rac)-PtdEG-d71	Isotope-Labeled Compounds	Others
16:0 (Rac)-PtdEG-d₇₁ is deuterium labeled 16:0 (Rac)-PtdEG.

16:0 (Rac)-PC-d80	Isotope-Labeled Compounds	Others
16:0 (Rac)-PC-d₈₀ is deuterium labeled 16:0 (Rac)-PC.

Gelsempervine A 16-epi-Nb-Methylvoacarpine	Others	Others
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .

HY-131729

16-Phenoxy tetranor Prostaglandin A2	Others	Cardiovascular Disease
16-Phenoxy tetranor Prostaglandin A2 is a metabolite of uprostone and an analog of the antifertility hormone PGF2α .

HY-117580

16α-Hydroxyprednisolone OH-PRED	Drug Metabolite	Inflammation/Immunology
16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes .

HY-146877S

16:0-18:1 PG-d31

Isotope-Labeled Compounds Others

16:0-18:1 PG-d₃₁ is deuterium labeled 16:0-18:1 PG.
HY-146878S

16:0-18:1 PG-d5

Isotope-Labeled Compounds Others

16:0-18:1 PG-d₅ is deuterium labeled 16:0-18:1 PG.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113344

16α-Hydroxyestrone 1 Publications Verification 16αOHE	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease .

HY-N1599

16-Epivoacarpine 16-epi-Voacarpine	Alkaloids other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Indole Alkaloids	Others
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .

HY-128378

16-Dehydroprogesterone	Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
16-Dehydroprogesterone is a steroidal progestin.

HY-N2431

16-Methoxystrychnine	Alkaloids Strychnos nux-vomica Linn. Classification of Application Fields Source classification Other Diseases Loganiaceae Plants Disease Research Fields Indole Alkaloids	Others
16-Methoxystrychnine is a alkaloid .

HY-N12542

16-Anhydrodeacetylnerigoside	Apocynaceae Structural Classification Natural Products Source classification Nerium indicum Mill. Plants	Others
16-Anhydrodeacetylnerigoside (compound 4) is a steroid that can be found in Nerium indicum .

HY-N11513

16-Epipyromesaconitine	Structural Classification Alkaloids Source classification Ranunculaceae Aconitum carmichaeli Debx. Plants	Others
16-Epipyromesaconitine is a natural product that can be obtained by the pyrolysis of Mesaconitine (HY-N0724) .

HY-116056

16-O-Methylcafestol	Structural Classification Terpenoids Coffea canephora Pierre ex Froehn. Source classification Rubiaceae Diterpenoids Plants	Others
16-O-Methylcafestol is a derivative of cafestol that can be isolated from green coffee beans .

HY-120894

16(R)-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
16(R)-HETE, a metabolite of the cytochrome P450 branch of the arachidonate cascade, is a vasodilator .

HY-N2992

16α-Hydroxytrametenolic acid	Other Terpenoids Classification of Application Fields Terpenoids Source classification Polyporaceae Poria cocos Plants Disease Research Fields Cancer	RAR/RXR
16α-Hydroxytrametenolic acid, a natural triterpene, is a potential retinoid X receptor (RXR) selective agonist .

HY-N7950

16-Oxoalisol A	Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae	Others
16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases .

HY-N9011

16-Oxo-11-anhydroalisol A	Triterpenes Source classification Alisma orinentale (Samuel.) Juz. Plants Alismataceae	Others
16-Oxo-11-anhydroalisol A is a triterpenoid from Alisma orientale .

HY-N2990

16α-Hydroxydehydrotrametenolic acid 3β,16α-Dihydroxylanosta-7,9(11),24-trien-21-oic acid	Triterpenes Classification of Application Fields Terpenoids Source classification Polyporaceae Poria cocos Plants Disease Research Fields Inflammation/Immunology	Others
16α-Hydroxydehydrotrametenolic acid is a triterpene Acid in fermented mycelia of edible fungus Poria cocos .

HY-137141

16-Keto Aspergillimide SB202327	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
16-Keto Aspergillimide (SB202327) is an anthelmintic agent isolated from Aspergillus strain IMI 337664 .

HY-N11486

16β-Hydroperoxyalisol B 23-acetate	Triterpenes Structural Classification Terpenoids Source classification Alisma orinentale (Samuel.) Juz. Plants Alismataceae	Others
16β-Hydroperoxyalisol B 23-acetate is a natural product that can be isolated from Alisma orientale .

HY-N3939

Gelsempervine A 16-epi-Nb-Methylvoacarpine	Structural Classification Alkaloids Source classification Pyridine Alkaloids Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth.	Others
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .

HY-N12530

16,17-EDT	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
16,17-EDT is an oxylipin and a metabolite of adrenic acid formed by the cytochrome P450 (CYP) pathway .

HY-N9533

16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid	Triterpenes Microorganisms Classification of Application Fields Terpenoids Source classification Other Diseases Disease Research Fields	Others
16R-Hydroxy-3-oxolanosta7,9(11),24-trien-21-oic acid is a lanostanoid that can be found in the Sri Lankan basidiomycete Ganoderma applanatum .

HY-W587691

16-Ketoestradiol 16-keto-17β-Estradiol	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
6-Ketoestradiol is an active metabolite of the endogenous estrogen estrone .

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-W491891

1,6-Dimethoxyphenazine	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,6-Dimethoxyphenazine is a metabolite of Streptomyces luteoreticuli K_ATOH et A_RAI .

HY-W050145

Levoglucosan 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose	Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .

HY-N9303

1,6-Dihydro-4,7'-Epoxy-1-Methoxy-3',4'-Methylenedioxy-6-Oxo-3,8'-Lignan	Natural Products other families Source classification Plants	Others
1,6-Dihydro-4,7'-Epoxy-1-Methoxy-3',4'-Methylenedioxy-6-Oxo-3,8'-Lignan is a Neolignan from stem bark of Ocotea veraguensis .

HY-N0992

1,6,7-Trihydroxyxanthone	Structural Classification Natural Products Goodyera oblongifolia Raf. Orchidaceae Source classification Plants	Apoptosis
1,6,7-Trihydroxyxanthone is a potent anticancer agent. 1,6,7-Trihydroxyxanthone inhibits cell proliferation and induces cell Apoptosis. 1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16 .

HY-N9300

1,6-Dihydro-4,7-epoxy-1-methoxy-3,4-methylenedioxy-6-oxo-3,8-lignan	Source classification Magnoliaceae Lignans Plants Magnolia denudata Desr.	Others
1,6-Dihydro-4,7-epoxy-1-methoxy-3,4-methylenedioxy-6-oxo-3,8-lignan, a lignan derivative from the ethyl acetate soluble fraction of twigs of Magnolia denudate (Magnoliaceae), exhibits anti-platelet-activating factor (PAF) activity. PAF is a potent lipid mediator in inflammation and asthma .

HY-108635

C16-PAF 5+ Cited Publications PAF (C16)	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	p38 MAPK MEK ERK Endogenous Metabolite
C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by activating the PAFR. C16-PAF is a potent MAPK and MEK/ERK activator. C16-PAF induces increased vascular permeability .

HY-N12041

Axl-IN-16	Structural Classification Natural Products Microorganisms Source classification	TAM Receptor HIF/HIF Prolyl-Hydroxylase
Axl-IN-16 is a dual inhibitor of Axl/HIF. Axl-IN-16 induces fruiting body formation of Flammulina velutipes. Axl-IN-16 inhibits hypoxia-inducible factor activity and receptor tyrosine kinase expression .

HY-13629

Etoposide Maximum Cited Publications 81 Publications Verification VP-16; VP-16-213	Infection Structural Classification Monophenols Classification of Application Fields Sinopodophyllum hexandrum (Royle) Ying Source classification Lignans Phenols Phenylpropanoids Plants Berberidaceae Disease Research Fields	Topoisomerase Autophagy Mitophagy Bacterial Apoptosis Antibiotic
Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .

HY-113105

Estriol 16α-(β-D-glucuronide) Estriol 16-glucosiduronate	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Estriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy .

HY-N7422

Kauran-16,17-diol ent-Kauran-16β,17-diol	Liliaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Inflammation/Immunology Fritillaria cirrhosa	Apoptosis
Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC₅₀ of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages .

HY-114610

13Z,16Z-Docosadienoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Free Fatty Acid Receptor
13Z,16Z-Docosadienoic acid, a ω-6 polyunsaturated fatty acid, possesses anti-borreliae effect. 13Z,16Z-Docosadienoic acid, as a long-chain fatty acid (LCFA), is a free fatty acid receptor 4 (FFAR4 or GPR120, a LCFA receptor) agonist .

HY-N1596

Ent-16α,17-dihydroxykauran-3-one Ent-3-oxokaurane-16α,17-diol	Structural Classification Terpenoids Source classification Diterpenoids Euphorbiaceae Plants Euphorbia kansuensis Prokh.	Others
Ent-16α,17-dihydroxykauran-3-one is a diterpenoid, which can be isolated from the roots of Euphorbia ebracteolata .

HY-N1645

2,16-Kauranediol Kaurane-2β,16-diol	Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Euphorbiaceae Coniogramme japonica (Thunb.) Diels Plants Disease Research Fields	Others
2,16-Kauranediol, a diterpene compound, is a natural product that can be isolated from the aerial part of Euphorbia hirta .

HY-N11458

Raddeanoside R16	Structural Classification Natural Products Source classification Ranunculaceae Anemone raddeana Regel Plants	Others
Raddeanoside R16 is an oleanane-type saponin, that can be isolated from the rhizoma of Anemone raddeana .

HY-N3825

ent-Kaurane-3α,16β,17-triol	Structural Classification Terpenoids Source classification Euphorbia stracheyi Boiss. Diterpenoids Euphorbiaceae Plants	Apoptosis
ent-Kaurane-3α,16β,17-triol (Compound 3) is an anticancer agent. ent-Kaurane-3α,16β,17-triol induces apoptosis in HCT116 cells .

HY-N3814

ent-16β,17-Dihydroxykauran-19-oic acid	Structural Classification Terpenoids Source classification Diterpenoids Plants Compositae Tephrosia candida DC.	Others
ent-16β,17-Dihydroxykauran-19-oic acid is an anti-inflammatory agent, which can be isolated from Siegesbeckia pubescens herb. ent-16β,17-Dihydroxykauran-19-oic acid inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia .

HY-N2994

3-O-Acetyl-16α-hydroxytrametenolic acid	Triterpenes Classification of Application Fields Terpenoids Source classification Polyporaceae Poria cocos Plants Disease Research Fields Cancer	Others
3-O-Acetyl-16α-hydroxytrametenolic acid (Compound 3) is a triterpene found in Poria cocos, with anti-oxidant and anti-cancer activity .

HY-N3824

ent-Atisane-3β,16α,17-triol	Structural Classification Terpenoids Source classification Diterpenoids Euphorbiaceae Euphorbia sieboldiana Morr. et Decne. Plants	Others
ent-Atisane-3β,16α,17-triol is a compound that can be isolated from the acetone extract of roots of Euphorbia sieboldiana. ent-Atisane-3β,16α,17-triol is a natural control product .

HY-N10762

15,16-Dihydrotanshindiol C	Structural Classification Terpenoids Labiatae Source classification Samanea saman (Jacq.) Merr. Diterpenoids Plants	Thrombin
15,16-Dihydrotanshindiol C, a diterpenoid, is a potent thrombin inhibitor .

HY-N2989

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	Other Terpenoids Classification of Application Fields Terpenoids Source classification Polyporaceae Poria cocos Plants Disease Research Fields Inflammation/Immunology	NO Synthase
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells .

HY-N12175

3β-Hydroxytaraxast-20-en-16-one	Source classification Myrtaceae Eucalyptus grandis Hill ex Maiden Plants	Others
3β-Hydroxytaraxast-20-en-16-one is a natural product isolated from eucalyptol/alcohol extract .

HY-N3811

ent-11β-Hydroxyatis-16-ene-3,14-dione	Infection Classification of Application Fields Euphorbia boetica Terpenoids Source classification Diterpenoids Euphorbiaceae Plants Disease Research Fields	RSV
ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity .

HY-N3704

Δ16-Dehydroadynerigenin β-D-digitaloside	Structural Classification Source classification Plants Compositae Saccharides Monosaccharides Gueldenstaedtia verna (Georgi) Boriss.	Others
Δ ¹⁶-Dehydroadynerigenin β-D-digitaloside is a glycoside that can be isolated from the oven dried leaves of Nerium odorum. It is a heart-healthy component.

HY-N3815

ent-16-Kaurene-3b,15b,18-triol	Structural Classification Suregada multiflora (Jussieu) Baillon Terpenoids Source classification Diterpenoids Euphorbiaceae Plants	Others
ent-16-Kaurene-3b,15b,18-triol is a ent-kaurene diterpene. ent-16-Kaurene-3b,15b,18-triol has significant antiallergic activity on β-hexosaminidase release induced by Polyginseng antigen .

HY-126355

4,7,10,13,16-Docosapentaenoic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
4,7,10,13,16-Docosapentaenoic acid is an endogenous metabolite.

HY-N3810

ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid	Structural Classification Terpenoids Source classification Pteridaceae Diterpenoids Plants Pteris semipinnata L. Sp.	Tyrosinase
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds .

HY-125150

AL-3138 11-Deoxy-16-fluoro PGF2α	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology	Prostaglandin Receptor Endogenous Metabolite
AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production .

HY-141629

N-Palmitoyl-D-sphingomyelin Sphingomyelin 16:0	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Liposome Endogenous Metabolite
N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .

HY-N10291

10-Phenyl-[12]-cytochalasins Z16	Alkaloids Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
10-Phenyl-[12]-cytochalasins Z16 (Compounds 5) is a cytochalasin that inhibits wheat root elongation with an IC₅₀ of 17.35 μM .

HY-N11496

*17(13→14)-Abeo-ent-3S,13S,16-trihydroxystrob-8(15)-ene*	Structural Classification Terpenoids Source classification Bituminaria morisiana (Pignatti & Metlesics) Greuter Diterpenoids Plants Compositae	Others
17(13→14)-Abeo-ent-3S,13S,16-trihydroxystrob-8(15)-ene is a natural sesquiterpene lactone with anti-inflammatory activity .

HY-N1646

2,16-Kauranediol 2-O-β-D-allopyranoside 2β,16α-dihydroxy-ent-kaurane 2-O-β-D-allopyranoside	Classification of Application Fields Terpenoids Source classification Pteridaceae Other Diseases Diterpenoids Plants Disease Research Fields Archidendron jiringa	Others
2,16-Kauranediol 2-O-β-D-allopyranoside (compound 26) is a natural product that can be isolated from the air-dried fronds of Pteris cretica .

Cat. No.	Product Name	Chemical Structure

HY-146891S

16:0-16:0 PC-d31

16:0-16:0 PC-d₃₁ is deuterium labeled 16:0-16:0 PC.
HY-146914S

16:0-18:0-16:0 TG-d5

16:0-18:0-16:0 TG-d₅ is deuterium labeled 16:0-18:0-16:0 TG.
HY-113031S

16α-Hydroxydehydroepiandrosterone-d5

16α-Hydroxydehydroepiandrosterone-d₅ (16α-Hydroxy-DHEA-d₅) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone[1].
HY-146930S

16:1 SM (d18:1/16:1)-d9

16:1 SM (d18:1/16:1)-d₉ is deuterium labeled 16:1 SM (d18:1/16:1).
HY-163165S

16:0-19:2-16:0 TG-d5

16:0-19:2-16:0 TG-d₅ is the deuterium labeled triacylglycerols.
HY-146779S

16:1 Cholesteryl ester-d7

16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.
HY-146926S

16:0 Coenzyme A-d4

16:0 Coenzyme A-d₄ is deuterium labeled 16:0 Coenzyme A.
HY-142798S

16-Keto 17β-Estradiol-d5 (Major)

16-Keto 17β-Estradiol-d₅ (Major) is the deuterium labeled 16-Keto 17β-Estradiol (Major)[1].
HY-146918S

16:0 (Rac)-PtdEG-d71

16:0 (Rac)-PtdEG-d₇₁ is deuterium labeled 16:0 (Rac)-PtdEG.
HY-146924S

16:0 (Rac)-PC-d80

16:0 (Rac)-PC-d₈₀ is deuterium labeled 16:0 (Rac)-PC.
HY-146877S

16:0-18:1 PG-d31

16:0-18:1 PG-d₃₁ is deuterium labeled 16:0-18:1 PG.
HY-146878S

16:0-18:1 PG-d5

16:0-18:1 PG-d₅ is deuterium labeled 16:0-18:1 PG.
HY-146882S

16:0-18:1 PE-d31

16:0-18:1 PE-d₃₁ is deuterium labeled 16:0-18:1 PE.
HY-146885S

16:0-18:1 PS-d31 sodium

16:0-18:1 PS-d₃₁ (sodium) is deuterium labeled 16:0-18:1 PS (sodium).
HY-146896S

16:0-18:1 PA-d31 sodium

16:0-18:1 PA-d₃₁ (sodium) is deuterium labeled 16:0-18:1 PA (sodium).

HY-117580S

16α-Hydroxyprednisolone-d3
16α-Hydroxyprednisolone-d₃ is the deuterium labeled 16α-Hydroxyprednisolone. 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes[1][2].

HY-130046S1

16β-Hydroxy-17β-estradiol-2,4-d2

16β-Hydroxy-17β-estradiol-2,4-d₂ is the deuterium labeled 16β-Hydroxy-17β-estradiol-2,4[1].
HY-Y0860S

1,6-Dibromo-n-hexane-d12

1,6-Dibromo-n-hexane-d₁₂ is the deuterium labeled 1,6-Dibromo-n-hexane[1].

HY-W050145S

Levoglucosan-d7
Levoglucosan-d₇ is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[1][2].

HY-W050145S2

Levoglucosan-13C6
Levoglucosan- ¹³C₆ is the ¹³C labeled Levoglucosan[1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[2].

HY-W008625S

1-Bromohexadecane-16,16,16-d3

1-Bromohexadecane-16,16,16-d₃ is the deuterium labeled 1-Bromohexadecane[1].
HY-116865S

Equilenin-4,16,16-d3

Equilenin-4,16,16-d₃ is the deuterium labeled Equilenin-4,16,16.
HY-100354S

C16-Ceramide-13C16

C16-Ceramide- ¹³C₁₆ is a ¹³C-labeled Glycine ethyl ester monohydrochloride[1].
HY-146630S

17β-Dihydroequilenin-4,16,16-d3

17β-Dihydroequilenin-4,16,16-d₃ is the deuterium labeled 17β-Dihydroequilenin-4,16,16[1].
HY-146734S

17β-Dihydroequilenin 3-sulfate-4,16,16-d3 sodium

17β-Dihydroequilenin 3-sulfate-4,16,16-d₃ (sodium) is the deuterium labeled 17β-Dihydroequilenin 3-sulfate-4,16,16.

HY-N0830S1

Palmitic acid-15,15,16,16,16-d5
Palmitic acid-15,15,16,16,16-d₅ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-129242S1

Tempone-d16

Tempone-d₁₆ is the deuterium labeled Tempone[1].
HY-100354S3

C16-Ceramide-d9

C16-Ceramide-d₉ is deuterium labeled C16-Ceramide.
HY-100354S4

C16-Ceramide-d31

C16-Ceramide-d₃₁ is deuterium labeled C16-Ceramide.
HY-N2427S

Adamantane-d16

Adamantane-d₁₆ is the deuterium labeled DL-Histidine[1].
HY-146736S

17β-Dihydroequilin 3-sulfate-2,4,16,16-d4 sodium

17β-Dihydroequilin 3-sulfate-2,4,16,16-d₄ (sodium) is the deuterium labeled 17β-Dihydroequilin 3-sulfate-2,4,16,16.
HY-B0282AS3

Acetylcholine-d16 bromide

Acetylcholine-d₁₆ (bromide) is the deuterium labeled Acetylcholine bromide[1].
HY-B1870S

Metaldehyde-d16

Metaldehyde-d₁₆ is a deuterium labeled Metaldehyde (HY-B1870).
HY-146631S

4-Hydroxy-17β-estradiol-1,2,16,16,17-d5

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].
HY-W010112S2

4-Pentylphenol-d16

4-Pentylphenol-d₁₆ is the deuterium labeled 4-Pentylphenol[1].

HY-B0312S1

Dipyridamole-d16
Dipyridamole-d₁₆ is the deuterium labeled Dipyridamole. Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.

HY-141570S

Lyso-PAF C-16-d4

Lyso-PAF C-16-d₄ is the deuterium labeled Lyso-PAF C-16[1].

HY-N8015S

Octanal-d16
Octanal-d₁₆ is the deuterium labeled Octanal[1]. Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells[2].

HY-116258S

C16 Ceramide-d7

C16 Ceramide-d₇ is the deuterium labeled C16 Ceramide[1].
HY-146944S

12-PAHSA-13C16

12-PAHSA- ¹³C₁₆ is ¹³C₁₆ labeled 12-PAHSA.
HY-146949S

D-Myo-phosphatidylinositol diC16-d5

D-Myo-phosphatidylinositol diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol diC16.

HY-139968S

13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d4
13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1-d₄ is the deuterium labeled 13,14-Dihydro-15(R,S)-hydroxy-16,16-difluoro Prostaglandin E1[1].

HY-129242S

Tempone-15N,d16

Tempone- ¹⁵N,d₁₆ is the deuterium and ¹⁵N labeled Tempone[1].
HY-146936S

C16:1 Ceramide-d7

C16:1 Ceramide-d₇ is deuterium labeled C16:1 Ceramide.

HY-W014787S1

Decanedioic acid-d16
Decanedioic acid-d₁₆ is the deuterium labeled Decanedioic acid[1]. Decanedioic acid, a normal urinary acid, is found to be associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency[2].

HY-146947S

D-Myo-phosphatidylinositol 4-phosphate diC16-d5

D-Myo-phosphatidylinositol 4-phosphate diC16-d₅ is deuterium labeled D-Myo-phosphatidylinositol 4-phosphate diC16.
HY-146826S

1,3-16:1 DG-d5

1,3-16:1 DG-d₅ is deuterium labeled 1,3-16:1 DG.
HY-146839S

17:0-16:1 PC-d5

17:0-16:1 PC-d₅ is deuterium labeled 17:0-16:1 PC.
HY-146851S

17:0-16:1 PE-d5

17:0-16:1 PE-d₅ is deuterium labeled 17:0-16:1 PE.
HY-146860S

17:0-16:1 PG-d5

17:0-16:1 PG-d₅ is deuterium labeled 17:0-16:1 PG.

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Species:	Human (118) Virus (14) Rhesus Macaque (4) Mouse (25) Rat (8) Cynomolgus (6) E.coli (1) Rabbit (2) Canine (2)
Tag:	SUMO (3) GST (10) Flag (5) NusA (1) His (136) Strep (3) Tag Free (20) Avi (30) Myc (4) HSA (1) MBP (1) Trx (2) Fc (18)
Source:	HEK293 (103) E. coli Cell-free (5) CHO (3) CHO (3) Sf9 insect cells (20) P. pastoris (4) E. coli (44)


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