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Art. -Nr.: HY-158018

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EGFR-TK-IN-2

EGFR-TK-IN-2 (compound 10b) is EGFR-TK inhibitor with the IC₅₀ of 0.16 μM. EGFR-TK-IN-2 inhibits cell growth.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₂H₁₉N₃O₃
Molecular Weight:373.40

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

EGFR-TK-IN-2 Chemical Structure

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Use of MCE Products

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

EGFR-TK-IN-2 (compound 10b) is EGFR-TK inhibitor with the IC₅₀ of 0.16 μM. EGFR-TK-IN-2 inhibits cell growth^[1].

Alle EGFR Isoform-spezifische Produkte anzeigen :

In Vitro

EGFR-TK-IN-2 (compound 10b) inhibits cell growth with the IC₅₀ values of 9.94 μM, 6.32 μM and 8.11 μM aganist HCT116, HePG-2 and MCF7, respectively.^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 373.40
Formel C₂₂H₁₉N₃O₃
SMILES

O=[N+](C1=CC(C2CC(C3=CC=C(OCC4=CC=CC=C4)C=C3)=NN2)=CC=C1)[O-]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Serag MI, et al. M. New oxadiazole and pyrazoline derivatives as anti-proliferative agents targeting EGFR-TK: design, synthesis, biological evaluation and molecular docking study. Sci Rep. 2024;14(1):5474. Published 2024 Mar 5. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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