Tyrosinase-IN-13
Tyrosinase-IN-13 (compound 3c), a derivative of Flurbiprofen (HY-10582), is a potent, non-competitive tyrosinase inhibitor (IC50=68 μM; Ki=36.3 μM). Tyrosinase-IN-13 is cytotoxic against hepatocellular carcinoma (HepG2), colorectal cancer (HT-29), and melanoma (B16F10).
For research use only. We do not sell to patients.
- Formula: C23H18ClFN4OS
- Molecular Weight:452.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 68 μM (Tyrosinase)[1]
Chemical Information
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Molecular Weight 452.93
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Formula C23H18ClFN4OS
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SMILES
FC1=C(C2=CC=CC=C2)C=CC(C(C)C3=NN=C(NC(NC4=CC(Cl)=CC=C4)=O)S3)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)