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  6. 19-Hydroxy-10-deacetylbaccatin III

19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively.

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19-Hydroxy-10-deacetylbaccatin III Chemical Structure

19-Hydroxy-10-deacetylbaccatin III Chemical Structure

CAS No. : 154083-99-5

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19-Hydroxy-10-deacetylbaccatin III Related Antibodies

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Description

19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].

Molecular Weight

560.59

Formula

C29H36O11
CAS No.
SMILES

CC(O[C@]12[C@]3([H])[C@](C([C@@H](C4=C(C)[C@@H](O)C[C@@](O)([C@H]3OC(C5=CC=CC=C5)=O)C4(C)C)O)=O)([C@H](C[C@@]1([H])OC2)O)CO)=O
Structure Classification
Initial Source
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

19-Hydroxy-10-deacetylbaccatin III154083-99-5OthersA498NCI-H226A549PC-3Inhibitorinhibitorinhibit

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