154083-99-5
Chemical Structure
19-Hydroxy-10-deacetylbaccatin III
- CAS No.: 154083-99-5
- Formula:C29H36O11
- Molecular Weight:560.59
InChIKey: LCBRTOBUIDCSID-ZHPRIASZSA-N
SMILES: CC(O[C@]12[C@]3([H])[C@](C([C@@H](C4=C(C)[C@@H](O)C[C@@](O)([C@H]3OC(C5=CC=CC=C5)=O)C4(C)C)O)=O)([C@H](C[C@@]1([H])OC2)O)CO)=O
Biological Activity: 19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively[1].
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19-Hydroxy-10-deacetylbaccatin III | 19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively. | |||||||||||||||||||||
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Keywords
