HIV-1 inhibitor-27
HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS.
For research use only. We do not sell to patients.
- CAS No.: 2302046-54-2
- Formula: C46H78N2O7
- Molecular Weight:771.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HIV-1 YU2 16 μM (IC50) |
HIV-1 NL4-3 0.5 μM (IC50) |
HIV-1 89.6 0.39 μM (IC50) |
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| TZM | CC50 |
128 μM
Compound: 5
|
Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTitre-Glo assay
Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTitre-Glo assay
|
[PMID: 35513221] |
Chemical Information
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CAS No. 2302046-54-2
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Molecular Weight 771.12
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Formula C46H78N2O7
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SMILES
[H][C@@]12CC(C)(CC[C@@]1(CC[C@@]3([C@@]2(C(C[C@@]4([C@]5(CC[C@@H](C(C)([C@@]5(CC[C@]43C)[H])C)O)C)[H])=O)[H])C)C(NCCCCCCCC(N[C@H]([C@H](CC(O)=O)O)CC(C)C)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)