SARS-CoV-2-IN-17
SARS-CoV-2-IN-17 (Compound 16) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-17 exhibits potent anti-viral activity with the EC50 of 2.18 μM. SARS-CoV-2-IN-17 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-17 is a potent NPro ligand.
For research use only. We do not sell to patients.
- CAS No.: 2761911-44-6
- Formula: C19H19F3N2O3
- Molecular Weight:380.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero C1008 | CC50 |
>200 μM
Compound: 16
|
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay
|
[PMID: 34749200] |
Chemical Information
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CAS No. 2761911-44-6
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Molecular Weight 380.36
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Formula C19H19F3N2O3
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SMILES
O=C(NC(C=CC=C12)=C2N(CC)CC3=C1C=C(OC)C(OC)=C3)C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)