Tyrosinase-IN-5
Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells.
For research use only. We do not sell to patients.
- CAS No.: 2525175-90-8
- Formula: C18H13N3O6
- Molecular Weight:367.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-F10 | IC50 |
143.2 μM
Compound: 16c
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Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability by MTT assay
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[PMID: 32652434] |
| HFF | IC50 |
194.1 μM
Compound: 16c
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Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HFF cells assessed as reduction in cell viability by MTT assay
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[PMID: 32652434] |
Chemical Information
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CAS No. 2525175-90-8
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Molecular Weight 367.31
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Formula C18H13N3O6
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SMILES
O=C1C=C(OCC2=CN(CC3=CC(C(O)=CO3)=O)N=N2)C4=CC=CC=C4O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tyrosinase-IN-5 Related Classifications
HY-143459 Related Classifications
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