Stearoyl-L-carnitine-d3 chloride
Based on 1 Customer Validation
Stearoyl-L-carnitine-d3 (chloride) is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 2245711-27-5
- Formula: C25H47D3ClNO4
- Molecular Weight:467.14
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-113147AS
L-Palmitoylcarnitine-d3 hydrochloride
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HY-130466
Stearoyl-L-carnitine chloride
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HY-113261
Oleoylcarnitine
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HY-113144AS
L-Hexanoylcarnitine-d3 chloride
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HY-132949S
Decanoyl-L-carnitine-d3 chloride
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HY-130321S
Lauroyl-L-carnitine-d3 chloride
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HY-N0391
L-Citrulline
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HY-N0391R
L-Citrulline (Standard)
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HY-130321
Lauroyl-L-carnitine chloride
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HY-139392S
Octanoyl-L-carnitine-d3 chloride
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HY-115704S1
Butyryl-L-carnitine-d3 chloride
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HY-W354498
L-Octanoylcarnitine hydrochloride
All Endogenous Metabolite Isoforms
More
Biological Activity
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GlyT2 |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2245711-27-5
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Unlabeled Cas 32350-57-5
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Appearance Solid
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Molecular Weight 467.14
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Formula C25H47D3ClNO4
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Color White to light yellow
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SMILES
CCCCCCCCCCCCCCCCCC(O[C@H](CC(O)=O)C[N+](C)(C)C([2H])([2H])[2H])=O.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
Ethanol : ≥ 20 mg/mL (42.81 mM)
DMF : ≥ 20 mg/mL (42.81 mM)
DMSO : ≥ 14 mg/mL (29.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Cristofano A, et, al. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia. PLoS One. 2016 May 19;11(5):e0155694. [Content Brief]
[3]. Carland JE, et, al. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. Br J Pharmacol. 2013 Feb;168(4):891-902. [Content Brief]
[4]. Huang W, et, al. Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells. Biochem Pharmacol. 1999 Oct 15;58(8):1361-70. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol / DMF | 1 mM | 2.1407 mL | 10.7034 mL | 21.4069 mL | 53.5171 mL |
| 5 mM | 0.4281 mL | 2.1407 mL | 4.2814 mL | 10.7034 mL | |
| 10 mM | 0.2141 mL | 1.0703 mL | 2.1407 mL | 5.3517 mL | |
| 15 mM | 0.1427 mL | 0.7136 mL | 1.4271 mL | 3.5678 mL | |
| 20 mM | 0.1070 mL | 0.5352 mL | 1.0703 mL | 2.6759 mL | |
| 25 mM | 0.0856 mL | 0.4281 mL | 0.8563 mL | 2.1407 mL | |
| Ethanol / DMF | 30 mM | 0.0714 mL | 0.3568 mL | 0.7136 mL | 1.7839 mL |
| 40 mM | 0.0535 mL | 0.2676 mL | 0.5352 mL | 1.3379 mL |
Stearoyl-L-carnitine-d3 chloride Related Classifications
HY-130466S Related Classifications
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