1. Metabolic Enzyme/Protease
    Neuronal Signaling
    Membrane Transporter/Ion Channel
  2. Endogenous Metabolite
    GlyT
  3. Stearoyl-L-carnitine chloride

Stearoyl-L-carnitine chloride 

Cat. No.: HY-130466
Handling Instructions

Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.

For research use only. We do not sell to patients.

Stearoyl-L-carnitine chloride Chemical Structure

Stearoyl-L-carnitine chloride Chemical Structure

CAS No. : 32350-57-5

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Description

Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].

IC50 & Target[2]

GlyT2

 

In Vitro

Stearoyl-L-carnitine (0.01-10 μM) inhibits glycine (30 μM) transports by 16.8% at concentrations up 3 μM in Xenopus laevis oocytes[2].
Stearoyl-L-carnitine (500 μM; 30 min) inhibits Na+-dependent [3H]carnitine (20 nM) uptake by ~50% in HPCT cells[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

464.12

Formula

C₂₅H₅₀ClNO₄

CAS No.
SMILES

CCCCCCCCCCCCCCCCCC(O[[email protected]@H](C[N+](C)(C)C)CC(O)=O)=O.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

References

Purity: ≥99.0%

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Keywords:

Stearoyl-L-carnitineEndogenous MetaboliteGlyTGlycine transportersendogenouslong-chainacylcarnitineGlyT2glycineInhibitorinhibitorinhibit

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Stearoyl-L-carnitine chloride
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