1. Metabolic Enzyme/Protease Neuronal Signaling Membrane Transporter/Ion Channel
  2. Endogenous Metabolite GlyT
  3. Stearoyl-L-carnitine chloride

Stearoyl-L-carnitine chloride 

Cat. No.: HY-130466 Purity: ≥98.0%
COA Handling Instructions

Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.

For research use only. We do not sell to patients.

Stearoyl-L-carnitine chloride Chemical Structure

Stearoyl-L-carnitine chloride Chemical Structure

CAS No. : 32350-57-5

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Stearoyl-L-carnitine chloride:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Stearoyl-L-carnitine chloride

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].

IC50 & Target[2]

GlyT2

 

In Vitro

Stearoyl-L-carnitine (0.01-10 μM) inhibits glycine (30 μM) transports by 16.8% at concentrations up 3 μM in Xenopus laevis oocytes[2].
Stearoyl-L-carnitine (500 μM; 30 min) inhibits Na+-dependent [3H]carnitine (20 nM) uptake by ~50% in HPCT cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Stearoyl-L-carnitine is significantly decreased in Alzheimer's disease (AD), mild cognitive impairment (MCI) and subjective memory complaint (SMC)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

464.12

Formula

C25H50ClNO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCC(O[C@@H](C[N+](C)(C)C)CC(O)=O)=O.[Cl-]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: ≥99.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Stearoyl-L-carnitine chloride
Cat. No.:
HY-130466
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