Lauroyl-L-carnitine chloride
Based on 1 publication(s) in Google Scholar
Lauroyl-L-carnitine chloride is an orally active metabolite. Lauroyl-L-carnitine chloride significantly reverses the decrease in its target gene IL-10. Lauroyl-L-carnitine chloride alleviates Crohn' s-like colitis.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 6919-91-1
- Formula: C19H38ClNO4
- Molecular Weight:379.96
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-113147A
L-Palmitoylcarnitine chloride
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HY-130466
Stearoyl-L-carnitine chloride
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HY-128974
N-Dodecyl-β-D-maltoside
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HY-B0762
Acetyl-L-carnitine hydrochloride
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HY-115704
Butyryl-L-carnitine chloride
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HY-N0391
L-Citrulline
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HY-W354498
L-Octanoylcarnitine hydrochloride
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HY-145542
Isovalerylcarnitine chloride
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HY-113147AR
L-Palmitoylcarnitine chloride (Standard)
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HY-N0391R
L-Citrulline (Standard)
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HY-B0762R
Acetyl-L-carnitine hydrochloride (Standard)
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HY-130466R
Stearoyl-L-carnitine chloride (Standard)
Publications Citing Use of MedChemExpress (MCE) Lauroyl-L-carnitine chloride
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
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IL-10 |
Microbial Metabolite |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6919-91-1
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Appearance Solid
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Molecular Weight 379.96
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Formula C19H38ClNO4
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Color White to off-white
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SMILES
CCCCCCCCCCCC(O[C@H](CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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iScience
Targeting Parkin-regulated metabolomic change in cartilage in the treatment of osteoarthritis. [Abstract]2024 Jul 27;27(9):110597. PMID: 39220257
Solvent & Solubility
DMSO : 50 mg/mL (131.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (3.29 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (3.29 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6319 mL | 13.1593 mL | 26.3186 mL | 65.7964 mL |
| 5 mM | 0.5264 mL | 2.6319 mL | 5.2637 mL | 13.1593 mL | |
| 10 mM | 0.2632 mL | 1.3159 mL | 2.6319 mL | 6.5796 mL | |
| 15 mM | 0.1755 mL | 0.8773 mL | 1.7546 mL | 4.3864 mL | |
| 20 mM | 0.1316 mL | 0.6580 mL | 1.3159 mL | 3.2898 mL | |
| 25 mM | 0.1053 mL | 0.5264 mL | 1.0527 mL | 2.6319 mL | |
| 30 mM | 0.0877 mL | 0.4386 mL | 0.8773 mL | 2.1932 mL | |
| 40 mM | 0.0658 mL | 0.3290 mL | 0.6580 mL | 1.6449 mL | |
| 50 mM | 0.0526 mL | 0.2632 mL | 0.5264 mL | 1.3159 mL | |
| 60 mM | 0.0439 mL | 0.2193 mL | 0.4386 mL | 1.0966 mL | |
| 80 mM | 0.0329 mL | 0.1645 mL | 0.3290 mL | 0.8225 mL | |
| 100 mM | 0.0263 mL | 0.1316 mL | 0.2632 mL | 0.6580 mL |
Lauroyl-L-carnitine chloride Related Classifications
HY-130321 Related Classifications
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