Lauroyl-L-carnitine-d₉ chloride

Name: Lauroyl-L-carnitine-d 9 chloride
Brand: MedChemExpress
SKU: HY-130321S1
Rating: 4.5 (1 reviews)

製品番号: HY-130321S1 純度: 98.0%: Data Sheet SDS COA 取扱説明書
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Lauroyl-L-carnitine-d₉ chloride is the deuterium labeled Lauroyl-L-carnitine chloride (HY-130321). Lauroyl-L-carnitine chloride is an orally active metabolite. Lauroyl-L-carnitine chloride significantly reverses the decrease in its target gene IL-10. Lauroyl-L-carnitine chloride alleviates Crohn' s-like colitis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Lauroyl-L-carnitine-d<sub>9</sub> chloride

Lauroyl-L-carnitine-d₉ chloride 構造式

CAS 番号 : 2245711-25-3

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 737	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 737	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solid
1 mg	$260	在庫あり	Estimated Time of Arrival: December 31
5 mg	$670	在庫あり	Estimated Time of Arrival: December 31
10 mg	$1070	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of Lauroyl-L-carnitine-d₉ chloride:

Lauroyl-L-carnitine chloride 在庫あり
Lauroyl-L-carnitine-d₃ hydrochloride 在庫あり

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

Interleukin Related アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

IC₅₀ & Target^[2]

IL-10

Microbial Metabolite

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[75].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

389.02

分子式

C₁₉H₂₉D₉ClNO₄

CAS 番号

2245711-25-3

Unlabeled CAS

6919-91-1

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCC(O[C@H](CC(O)=O)C[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O.[Cl-]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶剤 & 溶解度

体外:

DMSO : ≥ 10 mg/mL (25.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5706 mL	12.8528 mL	25.7056 mL
5 mM	0.5141 mL	2.5706 mL	5.1411 mL
10 mM	0.2571 mL	1.2853 mL	2.5706 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 98.0%

Select Batch:

データシート (271 KB) SDS (252 KB)

COA (247 KB) HNMR (304 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

[2]. Pei J, et al. Regulation of Plasma Metabolite-Inflammation Homeostasis Axes in IBD: Causal Evidence via Mendelian Randomization, in vivo and in vitro Validation[J]. Available at SSRN 5847951.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5706 mL	12.8528 mL	25.7056 mL	64.2640 mL
	5 mM	0.5141 mL	2.5706 mL	5.1411 mL	12.8528 mL
	10 mM	0.2571 mL	1.2853 mL	2.5706 mL	6.4264 mL
	15 mM	0.1714 mL	0.8569 mL	1.7137 mL	4.2843 mL
	20 mM	0.1285 mL	0.6426 mL	1.2853 mL	3.2132 mL
	25 mM	0.1028 mL	0.5141 mL	1.0282 mL	2.5706 mL