Tyk2-IN-16
Tyk2-IN-16 is a selective and potent TYK2 inhibitor with an IC50 of <10 nM for TYK2-JH2. Tyk2-IN-16 inhibits pSTAT4 with an IC50 of <10 nM in NK92 cells (WO2023220046A1; compound 184).
For research use only. We do not sell to patients.
- CAS No.: 3010874-30-0
- Formula: C20H20F2N8O
- Molecular Weight:426.42
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Tyk2 JH2 <10 nM (IC50) |
Chemical Information
-
CAS No. 3010874-30-0
-
Molecular Weight 426.42
-
Formula C20H20F2N8O
-
SMILES
N#CC1(CN(CC1)C2=NN(C3=C2C=NC(NC(C)=O)=C3)C4=NC=CC(C(F)(C)F)=N4)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)