3010874-30-0
Chemical Structure
Tyk2-IN-16
- CAS No.: 3010874-30-0
- Formula:C20H20F2N8O
- Molecular Weight:426.42
InChIKey: RCXXJWBXCJATGD-UHFFFAOYSA-N
SMILES: N#CC1(CN(CC1)C2=NN(C3=C2C=NC(NC(C)=O)=C3)C4=NC=CC(C(F)(C)F)=N4)C
Biological Activity: Tyk2-IN-16 is a selective and potent TYK2 inhibitor with an IC50 of <10 nM for TYK2-JH2. Tyk2-IN-16 inhibits pSTAT4 with an IC50 of <10 nM in NK92 cells (WO2023220046A1; compound 184)[1].
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Tyk2-IN-16 | Tyk2-IN-16 is a selective and potent TYK2 inhibitor with an IC50 of <10 nM for TYK2-JH2. Tyk2-IN-16 inhibits pSTAT4 with an IC50 of <10 nM in NK92 cells (WO2023220046A1; compound 184). | |||||||||||||||||||||
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Keywords