1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. (Z)-FeCP-oxindole

(Z)-FeCP-oxindole 

Cat. No.: HY-108444 Purity: 99.62%
COA Handling Instructions

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.

For research use only. We do not sell to patients.

(Z)-FeCP-oxindole Chemical Structure

(Z)-FeCP-oxindole Chemical Structure

CAS No. : 1137967-28-2

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 127 In-stock
Solution
10 mM * 1 mL in DMSO USD 127 In-stock
Solid
1 mg USD 85 In-stock
5 mg USD 175 In-stock
10 mg USD 280 In-stock
25 mg USD 565 In-stock
50 mg USD 905 In-stock
100 mg USD 1450 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM[1].

Molecular Weight

329.17

Appearance

Solid

Formula

C19H15FeNO

CAS No.
SMILES

O=C1/C(C2=CC=CC=C2N1)=C/[C-]34[Fe+2]56789%10%11([CH-]%12[CH]8=[CH]9[CH]%10=[CH]%11%12)[CH]3=[CH]5[CH]6=[CH]74

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (151.90 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0379 mL 15.1897 mL 30.3794 mL
5 mM 0.6076 mL 3.0379 mL 6.0759 mL
10 mM 0.3038 mL 1.5190 mL 3.0379 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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(Z)-FeCP-oxindole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Z)-FeCP-oxindole
Cat. No.:
HY-108444
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