(Z)-FeCP-oxindole
Based on 1 Customer Validation
(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.
For research use only. We do not sell to patients.
- Purity: 99.62%
- CAS No.: 1137967-28-2
- Formula: C19H15FeNO
- Molecular Weight:329.17
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All VEGFR Isoforms
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Biological Activity
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VEGFR2 200 nM (IC50) |
VEGFR1 |
Chemical Information
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CAS No. 1137967-28-2
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Appearance Solid
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Molecular Weight 329.17
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Formula C19H15FeNO
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Color Brown to reddish brown
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SMILES
O=C1/C(C2=CC=CC=C2N1)=C/[C-]34[Fe+2]56789%10%11([CH-]%12[CH]8=[CH]9[CH]%10=[CH]%11%12)[CH]3=[CH]5[CH]6=[CH]74
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (151.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0379 mL | 15.1897 mL | 30.3794 mL | 75.9486 mL |
| 5 mM | 0.6076 mL | 3.0379 mL | 6.0759 mL | 15.1897 mL | |
| 10 mM | 0.3038 mL | 1.5190 mL | 3.0379 mL | 7.5949 mL | |
| 15 mM | 0.2025 mL | 1.0126 mL | 2.0253 mL | 5.0632 mL | |
| 20 mM | 0.1519 mL | 0.7595 mL | 1.5190 mL | 3.7974 mL | |
| 25 mM | 0.1215 mL | 0.6076 mL | 1.2152 mL | 3.0379 mL | |
| 30 mM | 0.1013 mL | 0.5063 mL | 1.0126 mL | 2.5316 mL | |
| 40 mM | 0.0759 mL | 0.3797 mL | 0.7595 mL | 1.8987 mL | |
| 50 mM | 0.0608 mL | 0.3038 mL | 0.6076 mL | 1.5190 mL | |
| 60 mM | 0.0506 mL | 0.2532 mL | 0.5063 mL | 1.2658 mL | |
| 80 mM | 0.0380 mL | 0.1899 mL | 0.3797 mL | 0.9494 mL | |
| 100 mM | 0.0304 mL | 0.1519 mL | 0.3038 mL | 0.7595 mL |
(Z)-FeCP-oxindole Related Classifications
HY-108444 Related Classifications
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