Tyrosinase-IN-16
Based on 1 Customer Validation
Tyrosinase-IN-16 (compound 19a) is a tyrosine kinase (Tyrosinase) inhibitor with Ki=470 nM. Tyrosinase-IN-16 is cytotoxic to B16F10 cells, with >90% inhibition at 20 μM.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 126651-85-2
- Formula: C8H6BrN3S
- Molecular Weight:256.12
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 126651-85-2
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Appearance Solid
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Molecular Weight 256.12
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Formula C8H6BrN3S
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Color White to off-white
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SMILES
S=C1NNC(C2=CC=CC(Br)=C2)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (390.44 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9044 mL | 19.5221 mL | 39.0442 mL | 97.6105 mL |
| 5 mM | 0.7809 mL | 3.9044 mL | 7.8088 mL | 19.5221 mL | |
| 10 mM | 0.3904 mL | 1.9522 mL | 3.9044 mL | 9.7610 mL | |
| 15 mM | 0.2603 mL | 1.3015 mL | 2.6029 mL | 6.5074 mL | |
| 20 mM | 0.1952 mL | 0.9761 mL | 1.9522 mL | 4.8805 mL | |
| 25 mM | 0.1562 mL | 0.7809 mL | 1.5618 mL | 3.9044 mL | |
| 30 mM | 0.1301 mL | 0.6507 mL | 1.3015 mL | 3.2537 mL | |
| 40 mM | 0.0976 mL | 0.4881 mL | 0.9761 mL | 2.4403 mL | |
| 50 mM | 0.0781 mL | 0.3904 mL | 0.7809 mL | 1.9522 mL | |
| 60 mM | 0.0651 mL | 0.3254 mL | 0.6507 mL | 1.6268 mL | |
| 80 mM | 0.0488 mL | 0.2440 mL | 0.4881 mL | 1.2201 mL | |
| 100 mM | 0.0390 mL | 0.1952 mL | 0.3904 mL | 0.9761 mL |